ID A0A0V1ML87_9BILA Unreviewed; 1000 AA.
AC A0A0V1ML87;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Epidermal growth factor receptor kinase substrate 8 {ECO:0000313|EMBL:KRZ72319.1};
DE Flags: Fragment;
GN Name=EPS8 {ECO:0000313|EMBL:KRZ72319.1};
GN ORFNames=T10_7566 {ECO:0000313|EMBL:KRZ72319.1};
OS Trichinella papuae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268474 {ECO:0000313|EMBL:KRZ72319.1, ECO:0000313|Proteomes:UP000054843};
RN [1] {ECO:0000313|EMBL:KRZ72319.1, ECO:0000313|Proteomes:UP000054843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1980 {ECO:0000313|EMBL:KRZ72319.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the EPS8 family.
CC {ECO:0000256|ARBA:ARBA00006197}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ72319.1}.
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DR EMBL; JYDO01000080; KRZ72319.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1ML87; -.
DR STRING; 268474.A0A0V1ML87; -.
DR Proteomes; UP000054843; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01210; PTB_EPS8; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR039801; EPS8-like.
DR InterPro; IPR033928; EPS8_PTB.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR013625; PTB.
DR InterPro; IPR006020; PTB/PI_dom.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR041418; SAM_3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR12287:SF23; AROUSER, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR12287; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN; 1.
DR Pfam; PF08416; PTB; 1.
DR Pfam; PF18016; SAM_3; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00462; PTB; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:KRZ72319.1};
KW Receptor {ECO:0000313|EMBL:KRZ72319.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054843};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Transferase {ECO:0000313|EMBL:KRZ72319.1}.
FT DOMAIN 615..674
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 209..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 551..575
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 676..765
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 787..844
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 976..1000
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 676..690
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 707..750
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 751..765
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 787..804
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 811..844
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRZ72319.1"
SQ SEQUENCE 1000 AA; 112497 MW; 15F27BC6E093C897 CRC64;
LGIASMPVLG QNSYFRSSSS VGPLPASMNG NVRRLNGNFG GSMPSFVDGQ TFDVDMRKAY
MQEDSPSYFV EHLATFGVGP QFGLQWPSDG IRKLKQMERS SAIWAQRMIL RLRHTAVVVE
DENGDVVEQF PLNLVSEPTA HVSSDPRDLY NNLLVFIVNG SKGKKTATPT EMHIFQCVQV
SASEVADDIK QFLRGRFKAV PTGRRISGFA MPSGGLEGSP EMTTTDGTSL HGRSILSRSD
QRYFNQDRPR VNTVPVMMEN GRSPSNFNYR EIDQKSTFSD SSVEFFERDV NILNRCFDDI
ERFVARIQSA AIAQRELEAL QQQRRAMKPS SRSTQNRMPG DGILLMRAQL PPELEFFDIL
QKFKLCFNLL AKLKNHIHEP NAPELLHFLF TPLAIILDAC QWGFGRNIAP QVVSPLISRA
AKALLLNCLT SKESEIWASL GDAWRTTAEE WTGTLPGHYS PTFAHNYGPY STTTTAAVPD
SGQAVRQNRN LFIDAQLSGD FSRVSLERER LDFEKEKLQE EERRIQFEKR ILEEERRRLL
EEKRQFYEEQ EQRSVVSERL PRPPPAANGL YSSTMSRSRP DLYRETLREQ ESRRNFPPSN
VTDDVSFFFE QARARGSQIA QVVYERHGMN EKELTVRKGE FLEVLNNKKN WWECRNAHRQ
VGFVPHTILS VVDSGIHHNN SSTPHQQSKS FDEPLFVRPP PPSTSTFGPA MGNSGTAFGS
YATTEDDSAK RSSPVSRTAT PANNNGDTPE VIRQRRGKLD EPKNKEVMMF SSTCLVNSKR
PYVACAPPVP PPAPPPPPPP LPRTSSGSVE YDEKKASTSN GTIPHGLNTK ENGTSIRNGK
LPSNVTTVDS RRMLNEELLM TLNKSNLKGS FDFKAKPWPS SSLVTVQEMS SISSKQDVAE
WLQAKCFSGR AINLLREHDG EKLLSMNKVQ LEELIGREEG ARLYSQLQLQ KTTAKYLLKS
DSQLNSILAN RRNLNEEKMD DEKSLESQSD DVDSEITIAL
//
