ID A0A0V1MLA5_9BILA Unreviewed; 2068 AA.
AC A0A0V1MLA5;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Disks large-like protein 5 {ECO:0000313|EMBL:KRZ72615.1};
DE Flags: Fragment;
GN Name=DLG5 {ECO:0000313|EMBL:KRZ72615.1};
GN ORFNames=T10_13279 {ECO:0000313|EMBL:KRZ72615.1};
OS Trichinella papuae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268474 {ECO:0000313|EMBL:KRZ72615.1, ECO:0000313|Proteomes:UP000054843};
RN [1] {ECO:0000313|EMBL:KRZ72615.1, ECO:0000313|Proteomes:UP000054843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1980 {ECO:0000313|EMBL:KRZ72615.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ72615.1}.
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DR EMBL; JYDO01000076; KRZ72615.1; -; Genomic_DNA.
DR Proteomes; UP000054843; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00992; PDZ_signaling; 4.
DR CDD; cd11860; SH3_DLG5; 1.
DR Gene3D; 2.30.42.10; -; 4.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR035537; DLG5_SH3.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR PANTHER; PTHR46360; DISKS LARGE HOMOLOG 5; 1.
DR PANTHER; PTHR46360:SF1; DISKS LARGE HOMOLOG 5; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF00595; PDZ; 4.
DR SMART; SM00072; GuKc; 1.
DR SMART; SM00228; PDZ; 4.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 4.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR PROSITE; PS50106; PDZ; 4.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054843};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 2041..2057
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 818..893
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 912..976
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1471..1551
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1618..1683
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1852..2016
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
FT REGION 131..179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 389..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1101..1122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1309..1329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 346..387
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 554..616
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 692..719
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 755..827
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 132..155
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRZ72615.1"
SQ SEQUENCE 2068 AA; 229292 MW; 641C9722872852EA CRC64;
LMDHPQCLQS TSEKVTELGA AAADVAVVVG EESCSGAVCH SSTAASKESE DCIWTLSEQP
NDSTNELPTG VEAGTEMLAD ADNKPTLKHK TGDAEETNLN FEISRQAETR STATVLVKRE
LSPCALMASV QEQEEEELEV EEEEDDDDDV VEEPADESAA SYQQIQQGGG GRLPFGQFGR
SHELPPSMCL PWLSWSPLGR DRHASSSSYT HGDTIPKMRS SACLGMGGGL SSGAGLGGVT
VGGGSASGSL GQRDLDMSVG HLATVVANAQ NKRWSVAGAG PELTLLRVKL DDVQRELCEL
QSKHELMTLE YQDVLNELDC CRASKGRLEM ELHDCRLEAV KSKGDVELLV QQKQLAERQA
MELQLKLQAR QAELDDLRRH YAEMDNKDHR HYHHHHRRRD HEQQQQQQQQ KHEQLITSTL
MMEYEQACAE VAGLKDRCRL LEAETVELGS ALRLAQDECR HIRAGRERDL EQHRLKISSF
EECQVSLYQQ LHKIAQQRDI LRSENDMLKQ QLQDLCGDMT RNLNVRQKHE EAMRVLRRQH
DGVLSEYRHV MSERDSVLKE NERLSEEKGN LLKKVKSSES DRHALIEQLK TVEAQIEAVR
QERDALQQQL KARDEQLRDR LLAAATAYTT ASVGRQLMQA DAGDSGINPY MDPDQSITSA
ESVSELTSTA TTNATTTAAA GPTVGRRADA DYDKLRRLAD GLDEELTLVR QEVEAAKQQR
DWALGERQRI VSERESMRSM CDNLRKERDD AITRLAVAIR DSDEIMRQKD QAEREIRKIK
EKIEMDERRV TNVESTPSNS HDSAIDADMA EWEVETLELN MNGAQKNEDL GLQLRGGRDD
PVFGQLVPIY VTSVAVGSRL DGVLRIYDCI MMVNNIDVSL MERRSVMDIL RNSSAVKMVI
KRRRLVGMKL ISVPLAAASD GDVGIVFEDG VYVSKIKTSS AAAKAGHLAV GDRLVYINDV
PVENRSASTV EELVRSFNGC GLVLAVVKSP PVMSPITPSS STFPFQTSLS SSAQMRHQDS
CVNCQQSSAT AVSASAAAAS AAAVVVTKQK RDFAVQVSFV VTETQAPVKK YESLFDKMHD
KIFGRSERKA TVRAAAAVPI DTTDTPNESN KRWHGGQTSE RRARPSSVYS CYTVVDRSNS
KGGVTAEQQV LQQLDSILEA SERECDNNNN NNKALLLGVM NSERSGGGTW PKYKPNITGG
SVEMTNVANG TLEPPQAQAP TLAPAPAPTS DKFTGRRSAL QAFHGKIFDK QSAVESRLRN
TFAKRSSKIR STEARPVSYH PTSIIPSQYS LIGSKFSARP MSPLVGGNIH SISSSSPSDD
SPPQCLSLDN TAASSLHHAA AEHNLHVAHA MPVVTNKHRY SPCLAFDHQS PMANDVHDQD
IDQRSYASQS SGSRAAAVAG LFGSVAGDQQ SSSKSLHRLD AGRYHAAIHT LSRTKRVSNK
LDRVIPLHSF SSDEYNNQSG GGRLIKGDVR TLHIEKRSSH EGLGISVASS GNGVFVSSVS
ENSLAARHGL QVGDQLLEVC GINMRSANIQ HASNVLSHLG RSEQITLMVQ YNPNKYTREM
TDYHSVCSTP RATPSSMLST QGSKAFMSQD SSLQSTSATQ SHELLTGSHC SVHYEPRFVF
LKRDSDDWGF TLIGGNAIGI FVDDVKPVAC IVGPDSLRTG DQILEFDGVN FRKLTLEQAL
MEIGQRSVGS EVSVLVQYND SRYQKCKRGA GDSFYVRVTV DRQAENTDEL SFRSGDILRV
DNTVFNGVAG LWRAWLVDQE GRERSCGIIP SKNRLEEEFL FKRSGSEIST VEGTSTEGGG
GSRRGTIRRS LKFIRRSSRS SHQRTPSKES RDLESDSTII DELYQRVEHK QKRPLLLLGT
LVDVIVAKLL EDYPKMFVQC VPECVKPMPV PALEQGLLQN LYVDYRKRDK LFEITRVAVV
KDLIDKGYHC ILHVNPLAIE RLHRLQIYPV VIFVKFKNFK QIKELCDDRL SSKQAKEMFE
NAAKVEAECH HLFSATIHGP HHSIKHICQQ IACTVEHEQK KTLWIISGDT ILSSCYVAYT
YYYYIFYFIL ILVQCEWKGN HLSGKIKL
//
