ID A0A0V1MM92_9BILA Unreviewed; 870 AA.
AC A0A0V1MM92;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Transcription factor E2F4 {ECO:0000313|EMBL:KRZ72950.1};
GN Name=E2F4 {ECO:0000313|EMBL:KRZ72950.1};
GN ORFNames=T10_5892 {ECO:0000313|EMBL:KRZ72950.1};
OS Trichinella papuae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268474 {ECO:0000313|EMBL:KRZ72950.1, ECO:0000313|Proteomes:UP000054843};
RN [1] {ECO:0000313|EMBL:KRZ72950.1, ECO:0000313|Proteomes:UP000054843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1980 {ECO:0000313|EMBL:KRZ72950.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU003796}.
CC -!- SIMILARITY: Belongs to the E2F/DP family.
CC {ECO:0000256|ARBA:ARBA00010940, ECO:0000256|RuleBase:RU003796}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ72950.1}.
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DR EMBL; JYDO01000070; KRZ72950.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1MM92; -.
DR Proteomes; UP000054843; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd12238; RRM1_RBM40_like; 1.
DR CDD; cd12239; RRM2_RBM40_like; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 6.10.250.540; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR037241; E2F-DP_heterodim.
DR InterPro; IPR032198; E2F_CC-MB.
DR InterPro; IPR003316; E2F_WHTH_DNA-bd_dom.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR034147; RBM40_RRM1.
DR InterPro; IPR045164; RBM41/RNPC3.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR16105:SF0; RRM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR16105; UNCHARACTERIZED; 1.
DR Pfam; PF16421; E2F_CC-MB; 1.
DR Pfam; PF02319; E2F_TDP; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM01372; E2F_TDP; 1.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF144074; E2F-DP heterodimerization region; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50102; RRM; 2.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|RuleBase:RU003796};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU003796};
KW Reference proteome {ECO:0000313|Proteomes:UP000054843};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176};
KW Transcription {ECO:0000256|RuleBase:RU003796};
KW Transcription regulation {ECO:0000256|RuleBase:RU003796}.
FT DOMAIN 459..534
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 785..867
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
SQ SEQUENCE 870 AA; 96756 MW; 61BF1FC3FA0E7935 CRC64;
MVSKVIYKVW NMCSCTSEIG ESFVQKSESI PSVENDESTI SKIVLQTKRD VIDIGALDAE
TIETREHLDR ARRYNLTLSH LSGSPPFHQM SSSMILGAVT SVEMALTHPP LSEQALLRYH
RIAGDLMTAF SEMKIEPVEN VYVSFIMMSD DEEFDDVVEP GAYGHSSPIG ARAEKSLGLL
TQKFLKVLQE AKDGVVDLNV AADRLKVKQK RRIYDITNVL EGVGLIEKKS KNSVQWKGGA
VGKLGELNPS ATEALFNLKL ELTEQERVER SLDSHIKWLK QSIKNVIEAD NNSDAYYVNE
KELAAYIPGS TVFAIKADTG TDLEVPFPYK SENDTTVYAL LVKSEELPID VFLVRDLARE
INIDNLTMPD EDRFSKEVDP PVASPVTLQR TSSISGGAIS RALNGRNVSV KREPELLNQP
EITPVISEPK SKPWLIRLSP PASDEMITST FSYVDTLNCT LLVRHLPACL TDSDKMSLLS
QFGACRVRVM SSDGPLKHCA FASFRSVQEA RVALLQLHQL NVVGSRLVVT WARAEDRHWI
PTVWESAGSS SCASEELRGS LEQLARCLVE QKCPTVSQLA YSYPPPNRLA LRRITWCLEK
YPEFYTQVLH LMNKLCLPCP FDDDDDQWIA AEMEDDQPEA ELTGRCWVPG KQSIGSTDRD
HLKKQIKAIK RALPAKVAPR IVDAVPGAVR SAAATKRPAL RFATVHLRPP PADDGPTLLH
CPGGFGTFGP APLPKEEAAG ISGCEVAAEP LPLVSIEEIQ RNRVDQEQMK LLPAFKHYSP
GERCSRLYVK NLSKRVTDTE MRRIFGNFVQ DAESQHHQLH VKVMQTGRLR GQAFLAFGSV
EQAEAALHHC NGYILHGKPM VVAFSRSRLN
//
