ID   A0A0V1MZD8_9BILA        Unreviewed;       852 AA.
AC   A0A0V1MZD8;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   22-FEB-2023, entry version 13.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   Name=unc-32 {ECO:0000313|EMBL:KRZ76917.1};
GN   ORFNames=T10_9645 {ECO:0000313|EMBL:KRZ76917.1};
OS   Trichinella papuae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=268474 {ECO:0000313|EMBL:KRZ76917.1, ECO:0000313|Proteomes:UP000054843};
RN   [1] {ECO:0000313|EMBL:KRZ76917.1, ECO:0000313|Proteomes:UP000054843}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS1980 {ECO:0000313|EMBL:KRZ76917.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-ATPase), a
CC       multimeric enzyme that catalyzes the translocation of protons across
CC       the membranes. Required for assembly and activity of the V-ATPase.
CC       {ECO:0000256|RuleBase:RU361189}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|ARBA:ARBA00009904, ECO:0000256|RuleBase:RU361189}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRZ76917.1}.
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DR   EMBL; JYDO01000024; KRZ76917.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0V1MZD8; -.
DR   Proteomes; UP000054843; Unassembled WGS sequence.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629:SF63; V-TYPE PROTON ATPASE SUBUNIT A; 1.
DR   PANTHER; PTHR11629; VACUOLAR PROTON ATPASES; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Hydrogen ion transport {ECO:0000256|ARBA:ARBA00022781,
KW   ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW   ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054843};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM        403..427
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        448..466
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        536..556
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        568..589
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        652..671
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        781..805
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   COILED          51..121
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   852 AA;  97327 MW;  8B4B91BC29BBD3B9 CRC64;
     MGSLFRSEEM CRCQLFLQTE ASYACVSELG ELGLVQFRDL NPDVTAFQRK FVNEIRRCDE
     MERKLRFLEK EIKKDRIPIL DTSENPDAPL AREMIDLEAT FEKLDNELRE VNMNEEMLKK
     NFLELTELKH ILRKTQAFFD EQENIQAMQS LHANDGNLGQ VNPALEYDGE LIVTGDHKES
     FGGKLNLDFV VGVILRERIP AFERLLWRAC RGNGDLVQKS VILIFFQGEQ LKSRVKKICE
     GFRATLYPCP ETPQERREMA IGVMTRIEDL KTVLGQTQDH RHRVLVAAAK NIRIWFTKVR
     KIKSIYHTLN LFNLDVTQKC LIAECWCPVA DLDKIQLALK RGTEESGSSV PSILNRMYTT
     EAPPTYNRTN KFTAGFQNIV DAYGVASYRE VNPALYTIIT FPFLFAIMFG DFGHGLIMFL
     FALFLIVKEK QLIARKIRDE VFNIFFGGRY IIFLMGLFSI YTGIVYNEVY AKSVNIFGSS
     WMIPTEVDDN VLANVEKIQL NPNTSFLGHA YAYGLDPAWN IAVNKLNFLN SFKMKMSVII
     GVFQMLFGVV LSLFNYRFFN RKIDIYTMFI PQMLFMCCIF LYLCILIIYK WTVFSAAPAD
     MAVGHYPGSH CAPSLLIGLI FMFMFQQRNY GFGDSKCVTN AFYPGQVGFE QFLVVVAVLC
     APTMLFVKPY LIYRERKNRL KDGHIAIHAD MNSDDAEAVQ IKEKPSSSSS SASAGAHDEH
     DDMNISEIFI IQAIHTIEFC LGCISHTASY LRLWALSLAH AQLSDVLWAM VLRIAFGFQG
     YAGAIAVYLI VWAFGMLTIC ILVLMEGLSA FLHALRLHWV EFQSKFYTGS GYLFTPFSFD
     VILEQARIED GD
//