ID A0A0V1N582_9BILA Unreviewed; 637 AA.
AC A0A0V1N582;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Nuclear pore complex protein Nup50 {ECO:0000313|EMBL:KRZ79145.1};
GN Name=Nup50 {ECO:0000313|EMBL:KRZ79145.1};
GN ORFNames=T10_4781 {ECO:0000313|EMBL:KRZ79145.1};
OS Trichinella papuae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268474 {ECO:0000313|EMBL:KRZ79145.1, ECO:0000313|Proteomes:UP000054843};
RN [1] {ECO:0000313|EMBL:KRZ79145.1, ECO:0000313|Proteomes:UP000054843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1980 {ECO:0000313|EMBL:KRZ79145.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus, nuclear pore complex
CC {ECO:0000256|ARBA:ARBA00004567}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ79145.1}.
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DR EMBL; JYDO01000008; KRZ79145.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1N582; -.
DR STRING; 268474.A0A0V1N582; -.
DR Proteomes; UP000054843; Unassembled WGS sequence.
DR GO; GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
DR GO; GO:0046907; P:intracellular transport; IEA:InterPro.
DR GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd13170; RanBD_NUP50; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR015007; NUP2/50/61.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR000156; Ran_bind_dom.
DR InterPro; IPR045255; RanBP1-like.
DR PANTHER; PTHR23138:SF141; NUCLEAR PORE COMPLEX PROTEIN NUP50; 1.
DR PANTHER; PTHR23138; RAN BINDING PROTEIN; 1.
DR Pfam; PF08911; NUP50; 1.
DR Pfam; PF00638; Ran_BP1; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
PE 4: Predicted;
KW mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW Nuclear pore complex {ECO:0000256|ARBA:ARBA00023132};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein transport {ECO:0000256|ARBA:ARBA00023132};
KW Reference proteome {ECO:0000313|Proteomes:UP000054843};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Translocation {ECO:0000256|ARBA:ARBA00023010};
KW Transport {ECO:0000256|ARBA:ARBA00022816}.
FT DOMAIN 3..74
FT /note="Nuclear pore complex NUP2/50/61"
FT /evidence="ECO:0000259|Pfam:PF08911"
FT DOMAIN 515..628
FT /note="RanBD1"
FT /evidence="ECO:0000259|Pfam:PF00638"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 322..342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..26
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 637 AA; 70075 MW; C48D4C3FA6D52450 CRC64;
MKSKRTADSE LTREEFERDD EPRASEEQSS GPMAKASAEV IRKRLIKKVS RRSAANAEFT
GSNPFKNFTG FTNPEGYLKS KEPPVMPTPV SDPSNLEPVI EEPIIIISNI HKELSCSTVK
LVQNDSELQM KQKSALANVQ ALNSKWLMAM CEHFEKMPFL DFSKVAFDYI KEMRILIDIC
VALGIQLREE NQTLPKEQTT DVDSPSSYKH LSEILKPKDT SNVTLPEPKK IASVEEEKSD
KQKCMMKIYK VALPERSEAN QQMNTLKLKE TGAAKGLPFP VKLSQEIISE GASQKRLFKI
EQGIELIIGE KIVARKDENL TTEKKTDENS PSKSANCAKE SENSPSAALS VKNFSFNIKS
TTTASSSFGT TFGGALCDQL NKEVSASKLS FVFPSVSTSS PLAKPNLHFS SPTIAAAFGV
TTTTTATTST TTTTATTTTT VGSSLLMNLP QFSFLTGNAT SSTSKGQFNL FQFNQSNTAT
ATTTPSVFGG FAAASSEQED DEKYEPPKVE SVQVEEEGSV YSEKCKLYFK QDKEFVLKGI
GFVYLKPNDN GKVQLIIRDN TALGNLYLNI FLDELTPCQK INKNKIMLAA VPNPPIEGKS
EDEAVTYLIN MKSEKEADTL FDLINKAKAG VEVIFAF
//
