ID A0A0V1NAE7_9BILA Unreviewed; 1120 AA.
AC A0A0V1NAE7;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 13-SEP-2023, entry version 19.
DE SubName: Full=Solute carrier family 12 member 2 {ECO:0000313|EMBL:KRZ80821.1};
GN Name=SLC12A2 {ECO:0000313|EMBL:KRZ80821.1};
GN ORFNames=T10_6073 {ECO:0000313|EMBL:KRZ80821.1};
OS Trichinella papuae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268474 {ECO:0000313|EMBL:KRZ80821.1, ECO:0000313|Proteomes:UP000054843};
RN [1] {ECO:0000313|EMBL:KRZ80821.1, ECO:0000313|Proteomes:UP000054843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1980 {ECO:0000313|EMBL:KRZ80821.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ80821.1}.
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DR EMBL; JYDO01000001; KRZ80821.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1NAE7; -.
DR STRING; 268474.A0A0V1NAE7; -.
DR Proteomes; UP000054843; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015377; F:chloride:monoatomic cation symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR018491; SLC12_C.
DR InterPro; IPR004842; SLC12A_fam.
DR NCBIfam; TIGR00930; 2a30; 1.
DR PANTHER; PTHR11827:SF103; SODIUM CHLORIDE COTRANSPORTER 69, ISOFORM E; 1.
DR PANTHER; PTHR11827; SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS; 1.
DR Pfam; PF00324; AA_permease; 1.
DR Pfam; PF03522; SLC12; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054843};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 123..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 156..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 480..501
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 507..524
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 559..576
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 128..618
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
FT DOMAIN 627..1118
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..61
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1120 AA; 124727 MW; AA7C085E9765F196 CRC64;
MQNESGKENT ASGMVSKEAE LQTSSETKST PAELQKSSGT NSDSENEQIP ANNQNLPATE
PMPHLQNYAD KDVHHFTNLN LKKRPSLSQL HSDSVIHLDN IIDRKQEVPH LDGKQTKKVQ
QKLGWIEGVL IRSSLSVFGV IFYLRLTWIG AQAGIALGSI IIVLSSLIGL LTALSLSALC
TNGRVQSGGV YYIVSRTLGP EFGGSIGIIF CLANVTATAI TITGFAETVV SLMGRFHTQL
IDGEIMDIRI IGWITGCVLL MIVFTGVNFE AKAQIVLMVV LVASVLNYYI GTFIPVSEEQ
MARGVTGYDR NTLKSNFFPD WRGEDFFSIL AIYFPAVAGF MAGANISGDL KHPESAIPKG
TLWSMLITGG IYLSVLWITG SSVLRDASGS IEDLRDGTLT DCAANFTCQY GTQNSYEVLE
LEGAWGPLVT AGIFAASLSS ALGAMISGPK LFQAVAKDKL FPKIEFFAEG HGRNKEPRRA
IVLLFVISMA IIGIGRINII APIISNFFMA TYALINYACF DASFAKAPGF RPSFTFYNKW
MSLIGALICF GFMFLINWWA ALITTAFAIM LYVYLLRRKP DVNWGSSLEA NSYLSALRRM
LKLQFTRDHI KTYRPQILLL CGSPVRRPEL IDFVSNITKN SSLLICGHVI LGSPSEKVLE
VVDRYNKHMI VWLKSRRIYG FYSPVIAPNL SEGAHYLLQT AGMSYLKPNI LFLGYKNNWI
ESNAKEISEY FQLIHFAFDY DKALIILRLP KGFDISSLLN QETVNDSISD NVTAQGVHNV
RCKYIRSDGS SIIVSPLRMT ASMDSVFTDT VSINFAAYDN PRFHDSRLDV NSEKGIIDGN
PSFDLNDSEC IMHDRRYNSM RTNINDSEVD SSIDAASIRD LNFEIVTSNT HEALKGRKKS
TIISKVMKGD KWKKTLAGGQ QLNVFKNRIK KAVIDVWWLC DDGGLTILIP HLLTLERSYL
EEAKLRVFTV ATDAEKFEEQ KKELSNLLDS FRIDVKDVTV IPDISQEPKE STLNEFNQLI
SKFKVTDRNS SQLEEELLAV ATDDAELSML KYKTYQTLRI REELLENSKN ANLVVITLPV
PRRNGVSAAL YLSWLEMLSR DLPPTLLIRG NQKAVLTCEN
//
