ID   A0A0V1NH71_9BILA        Unreviewed;       484 AA.
AC   A0A0V1NH71;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 11.
DE   SubName: Full=Deoxyribonuclease-2-alpha {ECO:0000313|EMBL:KRZ83022.1};
DE   Flags: Fragment;
GN   Name=DNASE2 {ECO:0000313|EMBL:KRZ83022.1};
GN   ORFNames=T08_7899 {ECO:0000313|EMBL:KRZ83022.1};
OS   Trichinella sp. T8.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=92180 {ECO:0000313|EMBL:KRZ83022.1, ECO:0000313|Proteomes:UP000054924};
RN   [1] {ECO:0000313|EMBL:KRZ83022.1, ECO:0000313|Proteomes:UP000054924}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS272 {ECO:0000313|EMBL:KRZ83022.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DNase II family.
CC       {ECO:0000256|ARBA:ARBA00007527}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRZ83022.1}.
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DR   EMBL; JYDM01000234; KRZ83022.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0V1NH71; -.
DR   Proteomes; UP000054924; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004531; F:deoxyribonuclease II activity; IEA:InterPro.
DR   InterPro; IPR004947; DNase_II.
DR   PANTHER; PTHR10858; DEOXYRIBONUCLEASE II; 1.
DR   PANTHER; PTHR10858:SF23; DEOXYRIBONUCLEASE II; 1.
DR   Pfam; PF03265; DNase_II; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054924};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..484
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5006883371"
FT   TRANSMEM        356..373
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   NON_TER         484
FT                   /evidence="ECO:0000313|EMBL:KRZ83022.1"
SQ   SEQUENCE   484 AA;  54075 MW;  43B6EB7479D638F0 CRC64;
     MLLKLSKVFL IFNLINLSHS QTFTCRTNDV YKAPTQTTGK IIHAGAVGSW ANGQAPFTDP
     QGHSFAKTLE NVVRDNPTIK FLAYNNVPPG IPNVKTKSNS KGVIILSTAA DSAAWVIHTI
     PGFPTAKTPY AWPASETARG HLLICLTISK SQINAIAASL LLVQPVIHYN DIPETETAGM
     PYFKKLAEGQ TPIIPPFTSR RTIRSQNAAA PVTVHIYSKS ESSKYEIYKK VIVKALKKTI
     KVWSRRDNKL KGDCRVPERY IRLLQSPGVI NGHNTNIEAD DTNWAVSDPG SKNQSKEPAM
     AICIENNDIF TRFNEIAAQK RSSAIEGTAS IIKVGGPFHE AYVSRMNTLL DGIVDFLLYL
     NLFITCFLLF FFCRRKKARS RDVENYLSEP VTDVASENCE MEQSANVLNE ELDRHVEEEQ
     KPKQVVMLVE IEREKPKSGL YVEYTAEMKF RVNEESVQMY KPTLKKTVNV ADAGINAVQS
     FIMK
//