ID A0A0V1NIR7_9BILA Unreviewed; 883 AA.
AC A0A0V1NIR7;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Transcription factor E2F4 {ECO:0000313|EMBL:KRZ83889.1};
GN Name=E2f4 {ECO:0000313|EMBL:KRZ83889.1};
GN ORFNames=T08_13796 {ECO:0000313|EMBL:KRZ83889.1};
OS Trichinella sp. T8.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=92180 {ECO:0000313|EMBL:KRZ83889.1, ECO:0000313|Proteomes:UP000054924};
RN [1] {ECO:0000313|EMBL:KRZ83889.1, ECO:0000313|Proteomes:UP000054924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS272 {ECO:0000313|EMBL:KRZ83889.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU003796}.
CC -!- SIMILARITY: Belongs to the E2F/DP family.
CC {ECO:0000256|ARBA:ARBA00010940, ECO:0000256|RuleBase:RU003796}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ83889.1}.
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DR EMBL; JYDM01000193; KRZ83889.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1NIR7; -.
DR Proteomes; UP000054924; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd12238; RRM1_RBM40_like; 1.
DR CDD; cd12239; RRM2_RBM40_like; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 6.10.250.540; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR037241; E2F-DP_heterodim.
DR InterPro; IPR032198; E2F_CC-MB.
DR InterPro; IPR003316; E2F_WHTH_DNA-bd_dom.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR034147; RBM40_RRM1.
DR InterPro; IPR045164; RBM41/RNPC3.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR16105:SF0; RRM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR16105; UNCHARACTERIZED; 1.
DR Pfam; PF16421; E2F_CC-MB; 1.
DR Pfam; PF02319; E2F_TDP; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM01372; E2F_TDP; 1.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF144074; E2F-DP heterodimerization region; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50102; RRM; 2.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|RuleBase:RU003796};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU003796};
KW Reference proteome {ECO:0000313|Proteomes:UP000054924};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176};
KW Transcription {ECO:0000256|RuleBase:RU003796};
KW Transcription regulation {ECO:0000256|RuleBase:RU003796}.
FT DOMAIN 471..546
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 799..880
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
SQ SEQUENCE 883 AA; 98659 MW; 9D447EF5129BB7A3 CRC64;
MVMNEFTDRN RFPKQLDSCT SEICDSFVQK SESIPSVEDD ESTMTKIVLQ TKRDVIDIGA
LDAETIETRE HIDRARRYNL TLSHLSGSPP FHQMSSSMIL GAVTSVEMAL THPPLSEQTL
LRYHRIAGDL MTAFSDMKIE PVENVYVSFN DEEFDDVVEP GAYGHSSPIG ARAEKSLGLL
TQKFLKVLQE AKDGVVDLNV AADRLKVKQK RRIYDITNVL EGVGLIEKKS KNSVQWKGGA
VGKLGELNPS ATEALFNLKL ELTEQERVER SLDSHIKWLK QSIKNVIEAD NNSDAYYVNE
KELAAYIPGS TVFAIKADTG TDLEVPFPYK SENDTTVYAL LVKSEELPID VFLVRDLARE
INIDNLTMPD EDRFSKEVDP PVASPVALQR TSSISGGAIS RALNGRSVSI KREPELLNQP
EITPVICKQL FDFSFLFCSF QISLYTAEPK SKPWLIQMIT STFSYVDTLN CTLLVRHLPA
CLTDSDKMSL LSQFGACRVR VMSSDGPLKH CAFASFRSVQ EARVALLQLH QLNVVGSRLV
VTWARAEDRH CIPTVWESAG SSCASEELRG SLEQQLARCV VEQKCPTVSQ LAYRYPRPNR
LALRRISWCL EKYPEFYTQV LHLMNKLCLP CPFDDDDDQW IVADMEDDLP ETELTGRCWV
AEKQSIGSAD RDHLKKQIRA IRSGALPAKL APRTVGVVPR SAATKRPALQ FPTVRLRQLP
ADDRPTIFHC SGGFGTFGPA PLPKEKADIG GGEFSGAIKA AEPSLPLISV EEIQRNRVDQ
EQMKLLPAFK NYSPGERCSR LYVKNLSKRV TDAEMRCIFG NFVQNAESDH QFHVKVMQTG
RLHGQAFLAF GSVEEAEAAL QSCNGYILHG KPMVVAFSRS RLN
//
