ID   A0A0V1NK81_9BILA        Unreviewed;       482 AA.
AC   A0A0V1NK81;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   RecName: Full=DDRGK domain-containing protein 1 {ECO:0000256|ARBA:ARBA00018218};
GN   Name=PLCXD3 {ECO:0000313|EMBL:KRZ84062.1};
GN   ORFNames=T08_2812 {ECO:0000313|EMBL:KRZ84062.1};
OS   Trichinella sp. T8.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=92180 {ECO:0000313|EMBL:KRZ84062.1, ECO:0000313|Proteomes:UP000054924};
RN   [1] {ECO:0000313|EMBL:KRZ84062.1, ECO:0000313|Proteomes:UP000054924}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS272 {ECO:0000313|EMBL:KRZ84062.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DDRGK1 family.
CC       {ECO:0000256|ARBA:ARBA00009829}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRZ84062.1}.
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DR   EMBL; JYDM01000186; KRZ84062.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0V1NK81; -.
DR   Proteomes; UP000054924; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR019153; DDRGK_dom-contain.
DR   InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR   InterPro; IPR000909; PLipase_C_PInositol-sp_X_dom.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR13593:SF148; SI:DKEY-152B24.6-RELATED; 1.
DR   PANTHER; PTHR13593; UNCHARACTERIZED; 1.
DR   Pfam; PF09756; DDRGK; 1.
DR   SMART; SM01128; DDRGK; 1.
DR   SMART; SM00148; PLCXc; 1.
DR   SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50007; PIPLC_X_DOMAIN; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054924};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          64..226
FT                   /note="Phosphatidylinositol-specific phospholipase C X"
FT                   /evidence="ECO:0000259|SMART:SM00148"
SQ   SEQUENCE   482 AA;  56950 MW;  B31E3594E3D099F5 CRC64;
     MQTNTKILLS YTVIMIIGSY SFYLVRNYNF ENRKYYMKKR QEEKKRLYKM TQHNENWMRD
     LPLFLKLKPL THLFIPGSHQ SFSDLLNKKL PIATDVPKFL RFVDSPWARK IIERWGRCQE
     LHVTDQLRFG IRYFDVRVAF LPGECEQSLD IFLLHGLYGR PIKEVLDEIY TFISDHPEEI
     LILDINHFYN FNDELHRKFL IQLEHLFNGK FIPAPPSLSL NQVTVNFAQQ HGFQLLLFYQ
     QKLAEQFSFT WPSSYIASPW ANTNNLQHLW QYTENILTCR DQILPKGGFF VTQCILTPTW
     WNIVRHFKKS LRTVMATKTT EQAVSWLKKN SILLMPFFNI VIVDFVELFD FCTTVIQLNF
     HFEFLIYNVT LLFSVCILMY NDRFISIVNQ LSISFVVSME ELAGQFQMRS IDVIDRLKNL
     LADGMLTGVI DDRGKFIFVT EDEMKAIVTF VKQRGRVSVD DLVDYSNKLI NMDPQDVTLQ
     CS
//