ID A0A0V1NMH2_9BILA Unreviewed; 1087 AA.
AC A0A0V1NMH2;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500};
GN Name=NOP58 {ECO:0000313|EMBL:KRZ85206.1};
GN ORFNames=T08_4922 {ECO:0000313|EMBL:KRZ85206.1};
OS Trichinella sp. T8.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=92180 {ECO:0000313|EMBL:KRZ85206.1, ECO:0000313|Proteomes:UP000054924};
RN [1] {ECO:0000313|EMBL:KRZ85206.1, ECO:0000313|Proteomes:UP000054924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS272 {ECO:0000313|EMBL:KRZ85206.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Ligand for members of the frizzled family of seven
CC transmembrane receptors. {ECO:0000256|RuleBase:RU003500}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}. Secreted, extracellular space,
CC extracellular matrix {ECO:0000256|ARBA:ARBA00004498,
CC ECO:0000256|RuleBase:RU003500}.
CC -!- SIMILARITY: Belongs to the NOP5/NOP56 family.
CC {ECO:0000256|ARBA:ARBA00009211}.
CC -!- SIMILARITY: Belongs to the Wnt family. {ECO:0000256|ARBA:ARBA00005683,
CC ECO:0000256|RuleBase:RU003500}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ85206.1}.
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DR EMBL; JYDM01000148; KRZ85206.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1NMH2; -.
DR STRING; 92180.A0A0V1NMH2; -.
DR Proteomes; UP000054924; Unassembled WGS sequence.
DR GO; GO:0031428; C:box C/D RNP complex; IEA:InterPro.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0032040; C:small-subunit processome; IEA:InterPro.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0030515; F:snoRNA binding; IEA:InterPro.
DR GO; GO:0048699; P:generation of neurons; IEA:UniProt.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd13113; Wnt; 1.
DR Gene3D; 1.10.287.4070; -; 1.
DR Gene3D; 3.30.2460.20; -; 1.
DR Gene3D; 1.10.246.90; Nop domain; 1.
DR InterPro; IPR045056; Nop56/Nop58.
DR InterPro; IPR012974; NOP58/56_N.
DR InterPro; IPR042239; Nop_C.
DR InterPro; IPR002687; Nop_dom.
DR InterPro; IPR036070; Nop_dom_sf.
DR InterPro; IPR012976; NOSIC.
DR InterPro; IPR005817; Wnt.
DR InterPro; IPR043158; Wnt_C.
DR InterPro; IPR018161; Wnt_CS.
DR PANTHER; PTHR10894; NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58; 1.
DR PANTHER; PTHR10894:SF1; NUCLEOLAR PROTEIN 58; 1.
DR Pfam; PF01798; Nop; 1.
DR Pfam; PF08156; NOP5NT; 1.
DR Pfam; PF00110; wnt; 1.
DR PRINTS; PR01349; WNTPROTEIN.
DR SMART; SM00931; NOSIC; 1.
DR SMART; SM00097; WNT1; 1.
DR SUPFAM; SSF89124; Nop domain; 1.
DR PROSITE; PS51358; NOP; 1.
DR PROSITE; PS00246; WNT1; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473,
KW ECO:0000256|RuleBase:RU003500};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000054924};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687,
KW ECO:0000256|RuleBase:RU003500}.
FT DOMAIN 322..444
FT /note="Nop"
FT /evidence="ECO:0000259|PROSITE:PS51358"
FT REGION 560..754
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 625..653
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 691..706
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 707..722
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 733..754
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1087 AA; 125269 MW; C4D010E0A278A96A CRC64;
MTLKCSLMEI LGYGLMCRLD DLLFFSKRFA RQLQWHRRML LLYETASGYA IFRISEKFNL
TKVDDLWSEF ESPDKARQFV QLVNFRKFSD INQSLKSTMD IMENKCSKTL KKVIKKFVLP
EIQEKLAVAD AKLGNLIQEK FPGISCLSNS KITELFRGVR SNLNALLVDI PRRELENMAV
ALAHNMSRHK LKFTAEKIDM MIVQAIGLHD DLDRELNNYA MRCREWYGWH FPELGKCISD
HLLYAQIVER IGFRECAPMT NLSDLLSEDL QKKVKKMSLH SLGTEISTTD LKSIKLLCKQ
IIEISKYRTE LGNYLRARMF SLAPNLASLT GEIIGARLIA RAGSLLGLSK MSASTIQIIG
AEKALFRAIK TKRDTPKYGL IYHAQIISTV PQKLKGKVAR MLANKATLAV RYDALSEHTD
DGDMNILGLE QRAILEKRIK ALETGIAHQA TKTKKVRFRE APYIIQGGGE LYDTSADFTL
PRKRKHENDN ASDFIETKKL KLTSILKDEK KERSKKLTIQ GHQLAEEAQG YKVDKKMKKE
KHLKEESVFM EQPAVESFVE QEEMVESSVI VEEDSDKKKK KKKKKRTSDS ADITLESVEA
LGEIKTEPQL EIVEDVNVKK KKRKRKSGEE IESSEKKITV KEEKEKEEKR KDDDDDKDEE
EDSDLKNLSQ ELSVKSKKKK KMKKQQIEEE YEAKEEEEEE QQHLYGEDEG EESKLNLSTQ
STEKKKKKKK KKKNDSEVEQ WSFSNKKNDD NEAHMLPKSL RRQHFKDAWP RKEEACAPEI
LSIRRNRQLF VLCRHRPVLA KSLLSGLKEA VRECQFQMKH NRWNCSFGYH SMDYTLLDNP
PILNFGYKET SFLVALSSAG AAWSVARACA NGQLTSCTCN NRQHSSQQAW KWGGCSYSIK
FGLVNSRRLL TSKHSIHKAN LLKLVYKHNL KAGRMALKRT LKRDCKCHGI SGSCQMKTCW
KSPAEFREIG THLKKKLSRA MFILQNHSPN DSRYIAQQLK AAELVYFEQS PTYCEPLSHI
RSVGTRGRIC SVRNQTHSFA DCEIVCCGRG YFHQAELVVE NCNCKFHWCC QVMCDKCRRT
NWISKCR
//
