ID A0A0V1NVE9_9BILA Unreviewed; 3518 AA.
AC A0A0V1NVE9;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=WD repeat and FYVE domain-containing protein 3 {ECO:0000313|EMBL:KRZ87846.1};
GN Name=WDFY3 {ECO:0000313|EMBL:KRZ87846.1};
GN ORFNames=T08_7656 {ECO:0000313|EMBL:KRZ87846.1};
OS Trichinella sp. T8.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=92180 {ECO:0000313|EMBL:KRZ87846.1, ECO:0000313|Proteomes:UP000054924};
RN [1] {ECO:0000313|EMBL:KRZ87846.1, ECO:0000313|Proteomes:UP000054924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS272 {ECO:0000313|EMBL:KRZ87846.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ87846.1}.
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DR EMBL; JYDM01000094; KRZ87846.1; -; Genomic_DNA.
DR STRING; 92180.A0A0V1NVE9; -.
DR Proteomes; UP000054924; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd06071; Beach; 1.
DR CDD; cd15719; FYVE_WDFY3; 1.
DR CDD; cd01201; PH_BEACH; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR031570; NBEA/BDCP_DUF4704.
DR InterPro; IPR023362; PH-BEACH_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46108; BLUE CHEESE; 1.
DR PANTHER; PTHR46108:SF4; BLUE CHEESE; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF15787; DUF4704; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF14844; PH_BEACH; 1.
DR Pfam; PF00400; WD40; 1.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00064; FYVE; 1.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS51783; PH_BEACH; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000054924};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 2495..2622
FT /note="BEACH-type PH"
FT /evidence="ECO:0000259|PROSITE:PS51783"
FT DOMAIN 2650..2943
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REPEAT 3103..3144
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 3446..3506
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 15..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2403..2463
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3345..3370
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3518 AA; 393162 MW; B12A0638F46201D9 CRC64;
MVRKFSFVGA NEKSTSAQCN GASSTTENKN ASTSGATCNA SDSEKSSDHI LTLMHLRKVL
NELLRSANSS EDRDRKLYPV IRLFMKVCKV FTVEEITNRF KEAAQFVSLI SNFLVQEIRI
RAACPSTVEA AVEIVAYLKP TSDCSETKVS GWSMLYSLSF LLSSNKNCIV ESACKTSLPS
TLVKSLYLFC DLPKTCPLDE DQVRTLRGTL MKTMTVMLRN PRGIEQMASK DDLVLLFCGV
SSWCPVFNHT WRNCSAELLM TISSGVRSLL LINYIHTHKC IELFVDNLKH STQETIPDMV
EMICCLLCIL KDFASVSSLL LDDFENADGY KFLGDLVLQY ENVQRQNEQD SLRNLLFLVN
SVVSAGCDEI KLPEVQNPWK TSRPFHMPQP LGEGRTVRNM KAFELLETVF IHSRQTYICC
TILDVLYSML TADPVNYFIL ENRCPLGKFL ETLSTKSLKV QRKLFDLIEY VVFQLNYLPS
KEFIAIGPVL KMNKLYCGLF YLDCAVELLF FFFPFRDMAS IHLILGSLFK ILTYNPAVKD
VFREVGLLDV FITVLQNVYT SFNCCAEPNE QLWDTFTLTI NTLCLLVKQC NANVVLVREI
GGTKTVFAMV EDDCCRPLAL KLLQHIMMNP SGEDELAGVL ALLHSPTDNP ISLKSDVLQF
LSFVLRESHR VRMAFRRVGG YVYLLSLILN MGGTFKNLKK DFQHTDSFFE NFAYLRNIFK
VLTMSMRFEP SNAMFFQNEV KFNSLTDSLH LLGCFSEKRS FSVIPVKKGI AELRVDFLST
LCDIFNVAAD EKLSFPEGDL SENVVVICAI LRLLYDMAFD RSDRNGKVIE FTSEQPAHSP
NMISYRFASL IGQNAFVVHT GAVMCMFELL LYVEQPNPME TLNVQLFIIE MVKSILRTER
NQQVMCCVGL PRLLFDTVSD VFFEEEHPLL PPSYYILERL AAQGMTPNEL RSFLRLDKPW
CCADLDSDEP SGSNVVALNR VKTLVSMMTP KDLRLSLLNA SPPFVEFDMS IEGFGCIFLP
SIAPVGFGFV TGGLPLMHSN SQDGAVMNRG GLGNGERIFP PLAGLTYLCW VYVERFSESG
ADAHPLRLLT VYRTLASSHS HVGQPCHHQS RSLEPSTPPT LQGNSEIACL QMQISPVDRS
LIIATYETDT PGADLDKDVG SADGFVRLGI EELRRDRQWN HLAVVLNRSV LKSSTVTVYV
NGQQKASQRI QYVSHWPTMG TGAVASSLTT PQTCTVNALI GTAPGPFRKQ SSLLWRLSGA
YLVEEAMSSQ AVGQAYELGP HYTGSFQSPS SFLGRPMASL VTEERVSFGL HATAMSTMTL
ARLRKIYNKQ DSRAIGKLLG ISSHENITPV RLIHNSTVHL AGPARTLGGV LVGYLGMRTF
CAKSSAKLLE TVGGIACVLG LVSMADDTES LYAAIKALFF ALKTNRALNS EMEKIHGYQI
LTVLLKEKSR FLNTHVLYLL FSMVGTLDVT RETVVIPNTQ AFEDLFCDLQ VWNDASVDLQ
RLLYEHFYQL ITESGSHEEN LAIVRHVGLL PRLLYTLAYQ PHLLKATKDV IFNLISAILQ
PIADYTSLLK FGQFIIATLQ IKEMSNIEKS LPNDIQDLQA LLFNEDVEAE VDAATMRIAY
LVYIRNRCLN ILLNMLLNTS GKLNFQLCEQ ICKVLGFDWI LALFYGSNHK GTVRAGLQIL
LTIAKHSTLL NRFKEGVGNG GWLTDAESVV QNRAGVLLGF SVSARGSSVG SSCDLNLEIC
NLAGFVALQY LLPGHASLAE TQIACASLLV GHSARHLPTA HAQNVESIWS LIFNNAGDQA
VVTGAMGKLD LCPEASLPLL SVVRACVASN EFARTECSEQ NAVTLIQFVA FLYQNNSEFS
NYAQTSDFVV ALASTLLRPN SKCRNNIEEE TVRLTLPNHP AVRHVLELLS SIAIDGFLSG
QPNKHESVID ILLGPVQQST NTVEEFRPLV TAFLLNTMDR LEATDVLARG VGVPMCSPAA
PCTNYSILAA NIFYFAGKVV YCLWNDLFDG DSQSVFEFIL KLFAQVKRKS GPGVPLDALY
SSWNRCILFL LSRVLDDMKA QRTVVECLQK ITANRALLFS TANGEPEFFC CLAHLLFMLS
DVGGLQPQHK LDNETEKEEI EQRRLYDGRK LVSANAKRVW EELFLAKKQL LEETLGVTIM
PDVGASRAFA SAAASQQWLN FVDNEMKGCY GAKDALQIHI QLQSKLHMVT GGLQRLASKK
NIKSTGTARQ TVVSKQEFMM WLKVHVTLIH ELFDLQYTRY LQWHEHTKKW CLDEWTNLKQ
ELTRERGLWG PKNPSVLNKY MLDSTEGPCR MRMKMIPNIN FYVDYPYRPN VMNLENKTTK
NKLPCSSDSQ LYYERVKTRH GSCFDPRIID LSQPNSSKLE EGVQFDDAIV DVNAQMIKNT
IKRSATSVSS ADGDRDEANG TASSSDEPIS INDDVAVDDT ASSSVFSDSP QARPRDGSSF
SSSTLCSSAS VASEQSERLF LPKEPDSQTL LRLLEEGEEL NSMYRCARIC GLDSSEGLLL
FGKYHYYVID GFTLLKTREI RDLDFLPEEL HDPIVPYIAS GATRNRSQKR LCSKFAYEDI
RECHKRRYLL QPIAIEVFSS DGRNHLLAFP RKIRDKIYAK LLACAKSLTD AGHQSVSGQK
SGVDVEQGAG LLAVLMGEMS VTQRWVRGEI SNFQYLMHLN TLAGRSYNDL SQYPVFPWIL
SDYDSEELDL TNPNTFRDLS KPMGAQTPAR LEQFLKRFRE WDDPSGETPP YMYGTHYSSA
MIVVSYLVRV EPFTQQFLKL QGGHFDLADR MFHSVKDAWL SASRNNMADV KELVPEFFYL
PNFLLNSNHF ELGVKQSGLR LGDVILPPWA KGDAREFVRL HRQALESDYV SAHLNQWIDL
IFGYRQQGQA AVDAFNLFHH LFYEANVNFE AIEDPLTKNA TIGFINNFGQ IPSQLFKKPH
PVKRSLKSTL PLQHSISSNA ACAVAQQGVE GPTAAGPLFY HVAENLKPPL QPLRELKQAV
GHMAQNDKGA LLAVEQNKVL VPPQFHRYLA WGFPDNSIRL GSSDFDKSVC IHESPHWGDV
ICASCPNAHT AVTGSTCSVV CVWEIVGAAS RNQPAHLELR KRLYGHTEPV SCIYASTNFG
VIVSGSRDRT CIVWDLSKLS FIRQLGPHAG PVSAVSVNEA TGVIASCSGT HLHLWSFDGQ
KLAWVNTADS CKKSDMNEII ITITFSLLNE WDSQHVVAVG TNTGIVKLWT VKFVKVFDDC
SHVGRISSKS SSRSYCALFA AEPDRDSHCD MDHVAVEAVN AFSNNDHCDG LTNDKVSFTL
GNSNNSHSSE DDEQDSDAAF VDEGVSKVLP TSSCAEVVQS RNSEMVDIRR RSSESTMQKS
SEGADCCGDG EPQRKFHWER QLVFRGKLTM HTAFERKDNP APAAVTALMP SKDHKALYVG
DGRGRVWMWT VGDGHIGGRA DHWVQDPSRN LCSNCHQKFT LTDRRHHCRN CGQLFCSRCS
RFESEIRHLR IRRPVRVCQS CHARLKATDD SQSSNHAS
//
