ID A0A0V1P008_9BILA Unreviewed; 601 AA.
AC A0A0V1P008;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Ras-specific guanine nucleotide-releasing factor RalGPS1 {ECO:0000313|EMBL:KRZ89459.1};
GN Name=RALGPS1 {ECO:0000313|EMBL:KRZ89459.1};
GN ORFNames=T08_15032 {ECO:0000313|EMBL:KRZ89459.1};
OS Trichinella sp. T8.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=92180 {ECO:0000313|EMBL:KRZ89459.1, ECO:0000313|Proteomes:UP000054924};
RN [1] {ECO:0000313|EMBL:KRZ89459.1, ECO:0000313|Proteomes:UP000054924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS272 {ECO:0000313|EMBL:KRZ89459.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ89459.1}.
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DR EMBL; JYDM01000069; KRZ89459.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1P008; -.
DR Proteomes; UP000054924; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd13310; PH_RalGPS1_2; 1.
DR CDD; cd00155; RasGEF; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF368; RAS-GEF DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00617; RasGEF; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00147; RasGEF; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000054924}.
FT DOMAIN 99..335
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 356..388
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 425..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 439..453
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 601 AA; 68336 MW; C0A33F7B23146A03 CRC64;
MNIAVHKSII RLAAAFIVSS PKSFIAHRVD LHLRMYIDIF ELMERRSSRK YSMYDEGVTK
CLSWSTSAQC DDGAGYSPSA LKLQNRQFDP VTFNVLKVNP EDIAAQLTLG DLPIFKAIKP
DELTSCAWNS RNKLTVAPNV VAFIRRFNHV CLWCQKEILS CQSLKLRAEV LGHFLKISKK
LMDLNNIHSA FAIISGLQSS AVYRLYKTWA AVQTKDKAIY DKLTKLFSDQ NNWEKLRKYM
MTIKLPCIPY LGLYLTDLIY IDVAHPSSGG LESTQRLNMM NNILRVLADY QSSNYESLST
IDCFQSYLDS IRYIDELQKF VEEDLYNLSI KLEPNCNSSS VEKNFKHLLI SDTNGTPLKT
QSLTPQTSKS KQTHRKTQSL GGSNLVTKVP SIGNPLNETF PLTVDCRRHL LDDSLLEFSS
CTASSSSLQL PSNDVIGDSG HESSDENGIR LDLKGRSSSR DRLSRSVDTL EEECIIEGPA
KRKCILKNGH RPRFPVWRRF WIRLCGSALY VYESRNLPRN WNSRLAYKTY ASKIIALCGW
MVVKTDDPFM PDSFILQEPV LGIVYRLRVG TQANALRWVE KLKVACEDPR TKLPSNLISF
D
//
