ID   A0A0V1P1S0_9BILA        Unreviewed;       877 AA.
AC   A0A0V1P1S0;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 3A {ECO:0000313|EMBL:KRZ90133.1};
GN   Name=Smek1 {ECO:0000313|EMBL:KRZ90133.1};
GN   ORFNames=T08_4989 {ECO:0000313|EMBL:KRZ90133.1};
OS   Trichinella sp. T8.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=92180 {ECO:0000313|EMBL:KRZ90133.1, ECO:0000313|Proteomes:UP000054924};
RN   [1] {ECO:0000313|EMBL:KRZ90133.1, ECO:0000313|Proteomes:UP000054924}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS272 {ECO:0000313|EMBL:KRZ90133.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the SMEK family.
CC       {ECO:0000256|ARBA:ARBA00008809}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRZ90133.1}.
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DR   EMBL; JYDM01000060; KRZ90133.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0V1P1S0; -.
DR   Proteomes; UP000054924; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR006887; P4R3-like_central_dom.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR000697; WH1/EVH1_dom.
DR   PANTHER; PTHR23318; ATP SYNTHASE GAMMA-RELATED; 1.
DR   PANTHER; PTHR23318:SF0; SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3; 1.
DR   Pfam; PF04802; PP4R3; 1.
DR   Pfam; PF00568; WH1; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054924}.
FT   DOMAIN          17..103
FT                   /note="WH1"
FT                   /evidence="ECO:0000259|Pfam:PF00568"
FT   DOMAIN          185..375
FT                   /note="Serine/threonine-protein phosphatase 4 regulatory
FT                   subunit 3-like central"
FT                   /evidence="ECO:0000259|Pfam:PF04802"
FT   REGION          112..145
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          685..720
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          817..877
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        131..145
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        701..720
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        817..836
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        859..877
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   877 AA;  100369 MW;  456DD8283EF84761 CRC64;
     MSEPLVDDKC NDKDPSHRVK LYVLNEKRVW DDKGTGHVTC VFNERLQSHT LTVRSEQDGS
     ILLESKILNE TAYQKQQETL IVWTEADNSD FALSFQEKQG CDEVWRGICG AQGRDPAQES
     SDDTTQDSGS DEDSVENGAL NTVNSPTLQL PPCDLIHLKE INDVIAASFS AVSRRDALAF
     AIDGQQYIPK LIKLFHMVED LEDLESLHLL YRIFKNIFFL NKPPLFETLL SEQFLFDVIG
     ILEYDPTMQT RRKHREFLWE QAKFKEVVPI NSVPLLSKIH QVYRVQYIYD FIFPAPSIFE
     ENVLSTLSSF IFFTRVEIIN MLQEDKTFLA TLFALIKKKE ATVEEFQNVI GLLKEFCSYS
     PLLQAVHRES FFRTLMNNGI LDALEFFFQC DDSVVRSMAV DILNLIVDFD APAVRNYCII
     ESSATEEKLF LNLVIDLMNR DPDPDLVTTM HAYVVLKNLI DPETMPTATA QQRNDKHEFL
     SLFYRCCVPQ IFARFFPSIN GNKLIKDSYR NANLTNVYLE LLTFCIEHHS YHVRSLVLSR
     DLVAKILVFL QSRHMFLKLS ALRFFRKIVH HRDDFYNRHI IRHRLFDPVV KCFIANGSKY
     NVLNSALIEL FEFIRTENVR ILCLHFVENY MEHFEDVTYV NTFQGLKRRY EQQDSLSMKS
     SSHSSSGSLT DSASWRRIRN SRELDEEEQW LNDDDEDEWN SNGGTLNAEQ PRSSVISYPI
     GSKSSEGFTV TQPPGANAAS STAYSVDNGS EVNLPPLRSC DDDDDDDGIF FGPVKPKPKP
     HKIVIHSSSL AARLNAGENV HKETVAAVRA LVDYNDSDSD EEMDHQHQHD RDQFKGIDSG
     SAATAEEAKH DDSVESSSSS EQDLDLNSTP TKKARFQ
//