ID A0A0V1P745_9BILA Unreviewed; 770 AA.
AC A0A0V1P745;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 03-MAY-2023, entry version 21.
DE SubName: Full=Rho guanine nucleotide exchange factor 16 {ECO:0000313|EMBL:KRZ91803.1};
GN Name=ARHGEF16 {ECO:0000313|EMBL:KRZ91803.1};
GN ORFNames=T08_2503 {ECO:0000313|EMBL:KRZ91803.1};
OS Trichinella sp. T8.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=92180 {ECO:0000313|EMBL:KRZ91803.1, ECO:0000313|Proteomes:UP000054924};
RN [1] {ECO:0000313|EMBL:KRZ91803.1, ECO:0000313|Proteomes:UP000054924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS272 {ECO:0000313|EMBL:KRZ91803.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ91803.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JYDM01000040; KRZ91803.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1P745; -.
DR Proteomes; UP000054924; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR047271; Ephexin-like.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR12845:SF5; EPHEXIN, ISOFORM D; 1.
DR PANTHER; PTHR12845; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054924}.
FT DOMAIN 410..600
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 703..743
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 285..304
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 285..301
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 770 AA; 88117 MW; BCD93B6A33ED0204 CRC64;
MDTNSRRQNG IEEGKTGFEF TFFTGRNLRR SRREHFLLKI NCLDSISSSE GKPTSQKCSG
VGGRFFLFRP RSSFSNFSTS PHLHTVNCCS NDRSTWTVFG DPNSKSTTSP MRFSFKFEKI
ELVRSKSSRV QIFLLSISNF SSNRSNVPSI NFDQIQIRIE INRECNNNLH CKIGPIEEFR
SDIGKSDPKK EIGDENVTCN RVDWTPKRRR KNNLLGLDEA FSKLKLRGNR QHCDQSISKE
KCISNFPLKF VPKQSNNRNS DNRTIFSTPP PELVVVTFDS NFPQSNNNSA EQQSISPRNF
TKEKYNGKRN LNESEECKLR VKNVKQHKVF PFESYCSSLW RRKRSKGLPG SAEVSYMKNN
KSQQIEVSHS LLIVMLKVPP VCRLANLEAI VLCGTIDLGV LQTMGKDSIY LQEKIFEIVT
SEASYLNSLL ILTVHFMQSP KLSGKTDSES VITAQDHKEL FSSVHAVRHS SERLFKKLKQ
SVETSVMLDN ICDILADHLQ KDENVFVNYC RDLAYQQKKL HYLKENNAKF VEEIALLEKS
KLVKNQDLAS FLLQPLQRVT RYPLLIRAIR SQLNANDKRI ASVECALSIA QRVVSLCNES
RRHFQGIEEL FELHSKLIYN DQSPKQFPVI TRKRRLIMKG SFCASEIKKS KTSSANALLI
TKQTRDNFLV KDYCDRKSIA VPSFSFDPGT NGQTLLRFSA SFEHKFLVVL KSNHLNAEVR
ILLATNSQED KEKWIRALND PSYHCTVDIS SSVLCENLPN LFSKIKQSTN
//
