ID   A0A0V1P850_9BILA        Unreviewed;       646 AA.
AC   A0A0V1P850;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Protein lifeguard 1 {ECO:0000313|EMBL:KRZ92242.1};
GN   Name=GRINA {ECO:0000313|EMBL:KRZ92242.1};
GN   ORFNames=T08_15656 {ECO:0000313|EMBL:KRZ92242.1};
OS   Trichinella sp. T8.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=92180 {ECO:0000313|EMBL:KRZ92242.1, ECO:0000313|Proteomes:UP000054924};
RN   [1] {ECO:0000313|EMBL:KRZ92242.1, ECO:0000313|Proteomes:UP000054924}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS272 {ECO:0000313|EMBL:KRZ92242.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRZ92242.1}.
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DR   EMBL; JYDM01000036; KRZ92242.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0V1P850; -.
DR   STRING; 92180.A0A0V1P850; -.
DR   Proteomes; UP000054924; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd10428; LFG_like; 1.
DR   InterPro; IPR006214; Bax_inhibitor_1-related.
DR   PANTHER; PTHR23291; BAX INHIBITOR-RELATED; 1.
DR   PANTHER; PTHR23291:SF133; X-BOX PROMOTER ELEMENT REGULATED; 1.
DR   Pfam; PF01027; Bax1-I; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054924};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           28..646
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5006884031"
FT   TRANSMEM        89..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        134..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        159..183
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        189..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        221..243
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        255..276
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        373..393
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        405..424
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        436..456
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        462..481
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        493..515
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        521..544
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        556..575
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   646 AA;  72388 MW;  53A9F291AED549EE CRC64;
     MHERKLPTLN WALRTLHLCF RFTSTRAVYL WSVRLGEMKN CFCPHNNIPP TMQYPAAANV
     GKDNVEEGQD NIAIHFNDST IRSMFIQKVF LIVTAQLCVV SGVVALFTFN LFYLFSTLAI
     ALNDEVRRRY PMNFVLLGVL TVSLAIMAGT IASMVKSEVV MIAATVTCLT CLLVSLLAAF
     VKFDLTELLF PMYVIGIGLC VYGLVLMFFH TWFGISDVSH AFYSLMIIIF FLMYLAIDIQ
     LIMGNKKYSL SPEEYILAAM LLYVDIINIF INYVSLLSNQ PPYYNSYYVP GQAPPAPGWH
     APPPPQQGWQ QPPPTGGQYG YSQGGYPSYP PYPQTENAGV YSSHPAAENH GEDPKFGFGF
     SDKSIRQGFI RKVFLILTAQ LMVVTAMVAM FTYNDGVKGF VRRNLWTHWL ALVTFLVTYI
     VIGCCNNVRR RYPGNIICLA VLTLALGYIT GTTASFYDSQ TVILAILICC LCCGAVVIFS
     MQTKYDFTAC LGVVFMLSMG LFLFGILATI FTLAFRAPIV HVVYAGFAAV IFLIYLAIDV
     QMVVGGKRFE ISPEDYVFAA VQLLVDIVYI FLYLLEIIGY SKNVLYFTNR SYSPSGLGPE
     QFRLFSYVCE EKSKNVCNDE NLNCVKVHRV SAYIKIQLGQ AGFVDE
//