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Database: UniProt
Entry: A0A0V1PG10_9BILA
LinkDB: A0A0V1PG10_9BILA
Original site: A0A0V1PG10_9BILA 
ID   A0A0V1PG10_9BILA        Unreviewed;      4265 AA.
AC   A0A0V1PG10;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   28-FEB-2018, entry version 14.
DE   SubName: Full=Ryanodine receptor 44F {ECO:0000313|EMBL:KRZ94971.1};
GN   Name=Rya-r44F {ECO:0000313|EMBL:KRZ94971.1};
GN   ORFNames=T08_10827 {ECO:0000313|EMBL:KRZ94971.1};
OS   Trichinella sp. T8.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=92180 {ECO:0000313|EMBL:KRZ94971.1, ECO:0000313|Proteomes:UP000054924};
RN   [1] {ECO:0000313|EMBL:KRZ94971.1, ECO:0000313|Proteomes:UP000054924}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS272 {ECO:0000313|EMBL:KRZ94971.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KRZ94971.1}.
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DR   EMBL; JYDM01000015; KRZ94971.1; -; Genomic_DNA.
DR   Proteomes; UP000054924; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd00051; EFh; 1.
DR   CDD; cd12879; SPRY3_RyR; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   InterPro; IPR035762; SPRY3_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 2.
DR   Pfam; PF13499; EF-hand_7; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00054; EFh; 2.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 2.
DR   PROSITE; PS00018; EF_HAND_1; 2.
DR   PROSITE; PS50222; EF_HAND_2; 2.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Calcium {ECO:0000256|PROSITE-ProRule:PRU00448};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000054924};
KW   Receptor {ECO:0000313|EMBL:KRZ94971.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054924};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904}.
FT   DOMAIN      103    157       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      164    208       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      218    272       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      278    339       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      344    402       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      582    817       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1045   1226       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     4190   4225       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   DOMAIN     4228   4260       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   CA_BIND    4203   4214       {ECO:0000256|PROSITE-ProRule:PRU00448}.
FT   CA_BIND    4238   4249       {ECO:0000256|PROSITE-ProRule:PRU00448}.
FT   COILED     3384   3404       {ECO:0000256|SAM:Coils}.
FT   COILED     3880   3900       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   4265 AA;  484683 MW;  92DBEB37C676C75F CRC64;
     MTDFQENSTG EQDDISFLRT GDVVCLTCLA PCKESGTGSA ERVSLAAEGF GNRICYLENV
     SDKNKPPDNA TSMFYIDQAL SVRALQEMMS SESPNISGSS STHRTLLYGH AVQLKHALSG
     MYLTCLSTSS ASDKLAFDVG LCETNVGEFC WWTIHPASKQ RSEGEKVRFG DDVILVSVAT
     ERYLHMSSTN GNTVLAAFHQ TLWSITPNSS GGVRERHMGY VCGNDVLRLN HGNDECLTIP
     ENWSDSHQNN IVIYENGKSC NQARSLWRPE LIHGKWQSSL IGWEQAFRIR HITSGRFLAL
     NEDNQVCLLH KDRASFESTA FIMISSKDVK RSTFEEKEEE GMGVATVKYG ETVIFLQHLQ
     SNLWLSCQTT AVTKKNMGKV EEKKAIAVEE ARMDDCFILF KAQEEESQSA RVIRKCSQIL
     NRFLRGLEGL QMEGKDSLAW NRADLSETVK LMEDLIQYFA QPEESVDFES MQNGLRALRN
     RQDLFQEEGL LNMIIDTIDQ FSAVESMTEL LDVTKEDKCK NWQDISTYLY LLVAAMIKGN
     HSNCTQFASA QRLNWLFSRL SNPQSAEGIL DVLYCILTES PEALNMINED HVKAVISLLE
     KVGHDPKVLN VLSALCEGNG VAVRNSQNVI CSELLCNKKF LLQTKMIDQV SSVMANIFVG
     SYENSAMYPR WYFEAELEYM ESMRTSGQKP HLRIGWASSA GYRAYPGSGK KWGCNGVGDD
     MFSFGFDGQY IYAGIAALKL SKLIGGIEKF VGTHEIRKGD VIGCSIDLAI PEIQFSLNGH
     QIGTSVRNFS SCDCLFYPVM SLSAIVSCRF FFGGSQGKLR FGPKKGYLPI SEAAITPVKL
     ISCISFGDTR KGYFAGPSTV ISDYIVFQPK PIDTKDVSLP KHLEDVHEKL AENIHEVWAM
     DKIEKGWIYG ERRSETQKTH PCLTSYERLP TAERSYNLNL AKETLKTIVA LGYRIDIGKA
     SNRVKTFRLG QNFLMSNGYK PAPLDTREYE LNETLETLVD LLAKNMHNIW AQSKIQRGWT
     YSKNENVNIK TTSHLVAYDF LDPNIKAANR DKAGQIIRSL LVYNYCIEPP TAEQDEGAVK
     QSQVMNLQKR TYRFEKRYAV KSGKWYFEFE VRTSGFMNVG WMDVSASPDG DFGLHKSSYA
     YDGYLGRKWH GESESYGKKW NVGDVVGCFL DLTDRTICFS LNGELLLDSS GTEVAFDNVS
     AEDGFVPAFS LAPGQIGRLN CGQNVNTLKY YTTCGLQEGY EPFCIRMSRQ APMWIAKCEA
     EFDEINEEEK RFKVTRIPQS GDNPPCLKLQ CKSAGMLERC SLALFRLNLP VFCKEANDNR
     VCNQYFTETL SVRNAGKRNG ESDRTAESSR RGKMKGIRGS RNQDENISFH DQQNYADQYE
     VSNHAVMKSN YLVQKTFSLD DDSSEVTENR FRKAPRLRSS ASEANLKEKE SIDSQDKISA
     SYAVSNTKRN LRPFKVLQSF GQRMRDVSVG RSRKQNARKL QEACASKSKI RSDENDKFSS
     GHLNSRKLDD RVADVDSTES LDMPKSGPGR RPTVIRLESD SKVKKRSNYF SSGHDLLVEA
     SKLSAPSGNQ HVSIGASVSF YSTPDDYYFG VRVFPGQDLA NIWIGWLTPQ FSFTGSQIAA
     DSQRICFLES THSTLDNIQE FRSCYIVNGM ELLTAAGGSS SVSKMAGILA GCLINTATGE
     LKFHVNGKQT EMSYRVEPGT ILYPAVFVLP TSREVLQFEL GNIEKTLPIA SAQLNERSNA
     VQLMCPPRLK MEICKTRTWL RVPDQCARVT SLKLSDTRGW SVLCDDLVRT MMLYVPERDS
     SIDILELAEH ESLCTFHQQT LRLYCSLCAQ GNFKIAHILC QHVDEDQLMY AIQSKYLSGS
     LRQCFYDVLI AIHLKCHYDA RLAESHEYII PLNAKLKDRN YFNYETKSVY PHALNSDITL
     KSSINVMEVK KKISTEDEKF LMSPTFDFHT LKQYVVDALE EATLEALMNS RDLIGGTNTT
     HFLPILKLFD TLLLVGVLSD TDIHRFFRLL NPKSFQETLD SPQNVKGLVD LDLDEMVQLE
     LCHIMNHLCD LQLQGRVESL INFAETFDQL RRYLEIKQTD MPSAEAARKT KEFRCPPKEQ
     MLKLLDFKAD RDEQTDEEGE LEVSAMSEFL QRVLREFHCN MVKFIGNSDK NDDNYSANVE
     QKQLESENMN WVEKLAWMVV PVPPALLSED ERIKFDGEEA FRNIILSTLI KWTGNKAIDD
     PNLIREIFGL LLRQYTRISE VKSALKTAYC IHERSIEDVQ SFLDNLCQIR RLLCVQFEAT
     EEEVLKNSLW DMMNNKVFFQ HPDLMRLLKV HENVMTIMVN VLSRAQKSEL DDRRNRSTQD
     DMKKAFQNSI SDLVVACCKF LCFICRSSTK NQAAMFEHLP FLLDNATMLL AKPSLRGSVP
     LDVAYYSFME NSELALALKE DDLEKVAFYL SRCGLQANAE MVFKGYPDIG WDPVEGERYV
     DFLRFCVWVN GECVEENANL VIRLLIRRPE CLGPALKGQG EGLFRAFKDA ISLSSEISNL
     HKGRDLRSRF NFDLSHYPNP EIEEEDYIDL GAAILGFYSS LADLLGKCAP DHLTVKSGKG
     ESVRLRSILR SLTSVEDLEA ILALRFLLPN VFAAKEESSR SSSIGLLPCH KQSILLFLER
     VYGLIDKEMV FRLLEQSFIL DFRAATILDH PAYAESDLAL ALNRYLCGSV LPLLTSHAHC
     FADAEHYYSL LEATLHTVYR MSKIKSLTKS QRSAITEFLL AFTKEIHPGM MKKLLQKVVV
     DISSLNEFAT VPLQIMTQHY ECFSKHYGIS MHEDTASEEQ KRLSMLLFTT IFDSLGKRAF
     DSDLFASALP CLTAIGSALS PDYAMQSYAE EEIQNMNVPS GHMEVWRPHP VDASNVQLSV
     NLQNLVQRFA QHFHDSWASR KLEKGWRNDD IYSRTNCTHP RLKPFGMLKE FEQNFYKERC
     SECLKALLAW GYSIEQETQV SSVQPKSMNP TSNVRSASVF CPQPIDLSNM TLSEEMCELA
     ERIAENSHLI WVSKTIEDLN DANTGIMVLL VPWDILADSE KRKHRFRAQE VLKFLQYQGF
     RLKSPLHRAR EEYQQTVVDS NTHRPVEKRF ACNLLEKLLA YLENAAQKME VIKPSKQFSR
     YRNYTLPSED VKFFGKVLLP LLESYFRSHR NYFTAASSAS LSGVASIKEK EMVAGLFHRL
     MSVFRSKHNA FGCHVKSTVR CLQVLLQAID FRSLVKINSD TLRTCAQIFL SNMVSDLMNI
     TKEIKNNGRY AEIKGKTLPC TSSLLFLYEA MLPLLTTLFC HLSKHGHGQD FLVNDIQVGC
     YKIADCLYML ASPITISRKS VKEEMEKHRS SIGQCLSAFA CCFPVAFLEG DFNPNSRGST
     VDRQHLLSES KDTSSSLLLN IPSLDNLLSN IEQLSNTNGK YQDAPAIFDV DIPMLCSYMS
     FWWQHGPTNN TQEKNLSAVS SDHINRLFSA CSRLICDHIG IAHADWICHL APFITPMINY
     VTIEPVRDYL LPMAEKVRMQ ADLAFKEEEK HRMHPDVFDE STVIELHSIL IRDVYALYPI
     LIKFTDLHRA RWLKNPCWET NALFEHVAFV FKLWSTSQHM KREELNFITQ FESDFMTGTS
     RKTGKAAVAF RKKKRREGKR REKDSGSIVV ACLKRLLPVG LSVFGGRELD LLQKVKEKYM
     KKENDEKIKE YISSSLAVPD QEDVFDKSHW QRKLYQQIGK AQMLGIDSMS QEMVLDKIIF
     MGVTLCNLHN VEHPQTFQAD AWRKIVSSQR KRAVVACFRM VALYSIPKHR CVNLFLSAYI
     EKWLKSEKVD EDLLISEVTV ASEGRMQRLR EDVEEVDEQC PPDPLSQLVQ CFQRAATSER
     KQLVPIVDDN LYIQYVRVMA SSIHINDDEQ NNAEDDAISM EAQELEKQQL LHEQSRLADR
     GVAVMVLMYL SACNGEPNVM VEKTLALGIH ILNGGNSDVQ NIMLNYLQEK KDVRFFSSIS
     GLMNRCSVLN LEIFERQLKA EGLGMGAELS VGKHQNLNDS EFICSLFRFI QLTCEGHNSE
     FQNYLRNQPG NTTSINLIIC TVDYLLRLQE SIMDFYWHFS SKEVVDEAGK AHFLKALSVC
     SQVFNTLTES IQGPCVGNQM ALANSRLWDA INGFFFLFAH MMDKLSKNHT QLELLREFLS
     LQKDMIVLML SMLEGNILNG SIGKQMVDTL AESQQNVQLI LKFFDMFLKL KDLTTSQAFQ
     EFDTNKDGWI SPKEFLRAME AQKMYSTEEI NYLMMCTDVN NDGKIDYMEF TERFHNPAKD
     IGCIQ
//
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