ID A0A0V7ZPA9_9CYAN Unreviewed; 608 AA.
AC A0A0V7ZPA9;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:KST66289.1};
GN ORFNames=BC008_25305 {ECO:0000313|EMBL:KST66289.1};
OS Mastigocoleus testarum BC008.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Hapalosiphonaceae;
OC Mastigocoleus.
OX NCBI_TaxID=371196 {ECO:0000313|EMBL:KST66289.1, ECO:0000313|Proteomes:UP000053372};
RN [1] {ECO:0000313|EMBL:KST66289.1, ECO:0000313|Proteomes:UP000053372}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BC008 {ECO:0000313|EMBL:KST66289.1,
RC ECO:0000313|Proteomes:UP000053372};
RA Guida B.S., Garcia-Pichel F.;
RT "Draft Genome of the Euendolithic (true boring) Cyanobacterium
RT Mastigocoleus testarum strain BC008.";
RL Genome Announc. 0:0-0(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KST66289.1}.
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DR EMBL; LMTZ01000098; KST66289.1; -; Genomic_DNA.
DR RefSeq; WP_027840637.1; NZ_LMTZ01000098.1.
DR AlphaFoldDB; A0A0V7ZPA9; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000053372; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR017790; Penicillin-binding_protein_2.
DR NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053372};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 67..238
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 271..588
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 608 AA; 67385 MW; 8AEC700F7DFCA723 CRC64;
MSLLQSSLYG GKKDTRTVGK GFQSVFLVLF TLTVTTGITC RLVYLQIFEG KNLRERAEAN
RIRIIPKQPE RGNIFDRNGK LLATTRYPHS VYLWPMAHKT ASWSLVGPRL EAILKIPQEE
ISKQLEEAGP NSSSLVRIAR DISIEQITAL KEYASELKNV EIHRDAVRFY PHGKHFAHVL
GYTRELTAEQ LKEKKKEGYR LGDVIGQKGV EKAFEKNLRG EWGGQRVEVD GKGRPLRVLG
EKQAKAGNDI KLTLDLDVQK AASKALKGRN GTIVALDPKT GGVLAMVSYP TFDPNVFTKQ
RVKAKEILNI LRGRNNPLLN RALRAYPPAS TFKIVTTAAG LESGKYSPRT VLPTYGSLTF
GGHRFGEWNH RGFGPLGFTG AMAWSSDTFF YQVGARVGGT TLVDWTRKFG FGKRTGFEFR
AEESRGLVPD NDYQLKTWKR PWTVGDSANM SIGQGALLAT PLQVAVMFAI PANDGYRVQP
HLIEDKAQIE KWRTSLGMKP STVKVIRDGL RQVVTKGTGT ILNKPIIPAT AGKSGTAEAW
KPNRVKANHA WFGAYAPYNK PEIVVVAFGE HAGGGGSKIA APMVLEVLKD YFGRKYPNKY
NKPEAKKS
//
