ID A0A0V7ZV23_9CYAN Unreviewed; 1841 AA.
AC A0A0V7ZV23;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=BC008_32160 {ECO:0000313|EMBL:KST68038.1}, BC008_32965
GN {ECO:0000313|EMBL:KST68337.1};
OS Mastigocoleus testarum BC008.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Hapalosiphonaceae;
OC Mastigocoleus.
OX NCBI_TaxID=371196 {ECO:0000313|EMBL:KST68038.1, ECO:0000313|Proteomes:UP000053372};
RN [1] {ECO:0000313|EMBL:KST68038.1, ECO:0000313|Proteomes:UP000053372}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BC008 {ECO:0000313|EMBL:KST68038.1,
RC ECO:0000313|Proteomes:UP000053372};
RA Guida B.S., Garcia-Pichel F.;
RT "Draft Genome of the Euendolithic (true boring) Cyanobacterium
RT Mastigocoleus testarum strain BC008.";
RL Genome Announc. 0:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KST68038.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LMTZ01000083; KST68038.1; -; Genomic_DNA.
DR EMBL; LMTZ01000066; KST68337.1; -; Genomic_DNA.
DR RefSeq; WP_027842674.1; NZ_LMTZ01000083.1.
DR OrthoDB; 517727at2; -.
DR Proteomes; UP000053372; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43642; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR PANTHER; PTHR43642:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000053372}.
FT DOMAIN 13..273
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 1587..1838
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 1541..1578
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1841 AA; 209860 MW; CB95B73180A88BE1 CRC64;
MNIVCRSPII PGYQIREQLY AGSRTKVYRA LREQDSLAVV IKLLNSEYPS FNELLQFRNQ
YAIAKNLDIP GVIHPLSLET FGNGYILVME DKGEISLDEY IKTHRLSLVE FLSLGIQLAD
ILHNLYQNKV IHKDIKPANI LIDPETKQIQ LIDFSIASLL TKKTQEIKSP NLLEGTLAYI
SPEQTGRMNR GIDYRSDFYS LGITLFEMLA GQLPFISDDP MDLVHCHIAQ QAFRISDIKS
EIPEVISEVI SKLMAKNAED RYQSALGLKH DLETCLYQLK DSGEIRYFEI GQRDVCDHFL
IPEKLYGREV EVQELLDAFK RVTNGSSEIM LVAGFSGVGK TAVVNEVHKP MTHQRGYFIQ
GKFNQFNRNI PFSAFVQALR DLMGQLLSES DSQRLRWCTQ ILEAVGENGQ VLIEVIPELE
ALIGKQPPVS ELSGAAAHNR FNLLFQNFIA VFAKADHPLV IFLDDLQWSD AASMESIKIL
MSNSHLLLLG AYRDNEVSSV HPLMALLEKF KQAEVVINTI TLQSLSFDDT SRLVADILNC
STPCTDKSVS ARSRPLTEFI FRKTQGNPFF TTQLLKALYQ NGNIKFNRDD HYWEWDLTQI
DALFLTDDVV EFIAALLQKL SPETQKVLKL AACIGNHFDL ETLSIVYKKS YYQTARNLWE
SLQEGLVIPQ GEIYKFFSDD FFTFEFDTEK YVNQERSGKI FYKFLHDRVQ QAVYTLIEDN
QKKSVHLNIG RLLLSNLQCK SQEERLFEIV DHLNLGHELI TEERDIIELI KLNIHAGEKA
KKSTAYVAFR DYLRIAQEYI GKSGWDDNYE LSFNIHRLLA EAEQLNGNFQ ESENLILLSL
EKAQKKLEKA DLYNLFIIQY TMMGQGIMAV DIGRKSLHLF KINLPSTENI EKSLHNSFQN
VTSKIRDISF QSWLELPEST VPQQRICLQL LNSLLVPSYI SQQEKLHFWL GTKIVELSYQ
YGTVPASAYG FIVYGMFLGT ALANYKLGYD FGLLGLKLSR KYNKLDDITQ ACYIFGNNVY
AWNQPLQGSE KIFDEGIQAG LASGNFLFLG YILIYKLLNP FYQGKNLEEI ISNLPECLLF
VQKNNHQVGE DSILALDMII MNLLGHTSSL ESFDIDGCSE QKYLEKCQNN QSTYALCHYY
ILKSMLLYLY DRVTESLYYS EETKKIIAVL AAKYQVAVHI FYYSLNIISL YSKASKSQQE
KYWHKLSENQ EKMKLWAMNC PENFQHKFLL LEAEIARVTG KKIKAVNLYD HAIGKAKENK
YLQEEALANE LAAKFYLSWG KDKIAAVYMQ GACYCYSRWG AKAKVDHLEQ QYPYLLATIL
KTNNLNIKNS ANITSTSIEN VIRTSSSQNL SLDFPSVMKA AQAISQEIEL EKLLTTLMET
AIANAGAQSG HLILCQDDNQ WFVVIQADNK PKQVSTFQEQ VQGEQIQHLE IPLKRYQKIP
QSLIDLVRCT QKTAVFENLS SVVQFAGDHY IVTHKPKSVL CIPIIRQKKL IGILYLENNL
TLGAFTLDRI EILQLLTSQA AISIENARLY QKTENYSQIL KSEVKRKTRA LNQKAQDLEQ
ALRTLQRTQA QLIQNEKMSS LGQLVAGIAH EINNPISFIE GNLSYTKSYI EEMISLLGLY
QQEYPQPSSV IKGKCEEIDL DFLFEDVTKI IKSMESGSNR IKQIVLSLRN FSRLDESAIK
AVDIHSGIES TLLILQNRLQ GSENQREIKI IKEYCHNLPK ITCYPSELNQ VFLNIINNAI
DAIRDNTQRG ENPEIGIRTK AIDEKWVSIG IANTDSTIPV NIQERIFEPF FTTKAVGRGT
GLGLFVSYSI VQKHGGIVNV YSKPDEGTEF EIILPLQCAQ I
//
