ID   A0A0W0FD49_9AGAR        Unreviewed;      1321 AA.
AC   A0A0W0FD49;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=VPS10 domain-containing protein {ECO:0000259|SMART:SM00602};
GN   ORFNames=WG66_13155 {ECO:0000313|EMBL:KTB34253.1};
OS   Moniliophthora roreri.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Marasmiineae; Marasmiaceae; Moniliophthora.
OX   NCBI_TaxID=221103 {ECO:0000313|EMBL:KTB34253.1, ECO:0000313|Proteomes:UP000054988};
RN   [1] {ECO:0000313|EMBL:KTB34253.1, ECO:0000313|Proteomes:UP000054988}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MCA 2952 {ECO:0000313|EMBL:KTB34253.1,
RC   ECO:0000313|Proteomes:UP000054988};
RA   Aime M.C., Diaz-Valderrama J.R., Kijpornyongpan T., Phillips-Mora W.;
RT   "Draft genome sequence of Moniliophthora roreri, the causal agent of frosty
RT   pod rot of cacao.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KTB34253.1}.
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DR   EMBL; LATX01002101; KTB34253.1; -; Genomic_DNA.
DR   eggNOG; KOG3511; Eukaryota.
DR   Proteomes; UP000054988; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007034; P:vacuolar transport; IEA:UniProt.
DR   Gene3D; 2.10.70.80; -; 2.
DR   Gene3D; 3.30.60.270; -; 2.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR031777; Sortilin_C.
DR   InterPro; IPR031778; Sortilin_N.
DR   InterPro; IPR006581; VPS10.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR12106; SORTILIN RELATED; 1.
DR   PANTHER; PTHR12106:SF27; VPS10 HOMOLOG 1-RELATED; 1.
DR   Pfam; PF15902; Sortilin-Vps10; 2.
DR   Pfam; PF15901; Sortilin_C; 2.
DR   SMART; SM00602; VPS10; 2.
DR   SUPFAM; SSF110296; Oligoxyloglucan reducing end-specific cellobiohydrolase; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054988};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        1216..1238
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          2..554
FT                   /note="VPS10"
FT                   /evidence="ECO:0000259|SMART:SM00602"
FT   DOMAIN          580..1212
FT                   /note="VPS10"
FT                   /evidence="ECO:0000259|SMART:SM00602"
SQ   SEQUENCE   1321 AA;  147673 MW;  77E660C56AB72EF8 CRC64;
     MGISFIKEQS AIKMVGELFT YYTTDAFASK PKKLLSNTQR CQFAHSSKDF KHNAPADLVY
     CVAFDSTTST GATPSIESSK LFSSTDFFQS NKKVEDLGIG KNARGVVAFA IVSKFAVVAL
     QDLSQGGKGD MVLYVTVDTL TWARAEFPHA SSAKLRENAY TIVESTTHSL AVDVVMQDSG
     TIGTLFVSNS NGTYFTQSLK DTNRNEAGYV DYERIYGLEG VGLANIVANP DQVEGGWGVE
     KMLKSRITWD DGRSWKDIQP PLHDARGNRI NCNAKNKEEC SLHLHSVTAP HNFGRIFSSP
     APGIVMGVGN VGNTLLPYED CDTYLSTDAG VSWSQIRFGA HKYEFGDSGS ILVVVNDEET
     TDEVAYSLDL GKTWNTYRFG VKLRARALVT LPDSTSQKFI LVGQVSRKDQ TNNVGRFVTV
     FLDFADTRGR KCGDSDYEKW YARPRDKECL MGHKARFFST PTRLTEPRAN DPIEQEENCE
     CGDEDFECDF NYTPSGDQCV ALGPEPIPAG ICLDSNSKYM GSSGWRRIPG DTCVGGSKAD
     KDKKIEKDCT QAQPAEGEIR HQTFEFPDFI EQHAYFRDSK TLLVRLHNLA IYQSSNEGYT
     WQQIHPEERF LAFYHHPYSN ERAYLITAEN RMYVTTDTGR SWNKMETPTP PNRFRVPVLR
     FQPESDRIIW TGSVNCEGSQ QGCHAEAHWS RNNGRAWTLI DKYVVNCAWA ADTKLQADPT
     EIVCESWQQK EGNQPSQPGL GLELVEGKKY YAQGERKKLF DSVVGFAKFS EYLVVAELKP
     SGTSLELQVS LDGINFAPGV FPKGMMLDTH AYTVLESSTQ SLFLFMTMSD LPPFGSILKS
     NSNGTYFIDS LDNVNRNGEG YVDFEKMIGL DGIALVNVVK DPIEAAITGR KHLVSRITHN
     DGGTWKPLRP PSTDSLGNEY DCKDTSCALH VHGYTERLDP RATFSSPSIV GLIMAVGNVG
     SSLAPYKDSD TFLSRDGGFT WREVHKDAHL WEFGDSGSIL IMANDEEPVD HILFSIDEGE
     SWREYRFMAD GAGKMRVRFI VTVPSDTSRR FVLLGEYPGG RGSVAVQVDF SALTNRKCVL
     NTDDPNHDDF ELWSPSEERN EVCLFGRQTL YHRRTPKANC YVGDQAKAKV KIEKNCACTE
     SDFECEFNHV RDLETNKCVL VAGASPLPSD QQCQDDGMWY ERTAYRKIPH SSCEGGSRLD
     RGEGHYCPGN LAGHGFFFWF MVLAVPFGLT AMIGMWWWRK SGLARGMIRL PGDSRGLGQS
     GSGVLDTLAS VPWFLIGLAG IAYEWITEKI DRVGWRYKHR RGYRNLPVDE DAQILRFEDE
     E
//