ID A0A0W0GDW3_9AGAR Unreviewed; 1048 AA.
AC A0A0W0GDW3;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=PI3K/PI4K catalytic domain-containing protein {ECO:0000259|PROSITE:PS50290};
GN ORFNames=WG66_720 {ECO:0000313|EMBL:KTB46719.1};
OS Moniliophthora roreri.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Marasmiineae; Marasmiaceae; Moniliophthora.
OX NCBI_TaxID=221103 {ECO:0000313|EMBL:KTB46719.1, ECO:0000313|Proteomes:UP000054988};
RN [1] {ECO:0000313|EMBL:KTB46719.1, ECO:0000313|Proteomes:UP000054988}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCA 2952 {ECO:0000313|EMBL:KTB46719.1,
RC ECO:0000313|Proteomes:UP000054988};
RA Aime M.C., Diaz-Valderrama J.R., Kijpornyongpan T., Phillips-Mora W.;
RT "Draft genome sequence of Moniliophthora roreri, the causal agent of frosty
RT pod rot of cacao.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTB46719.1}.
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DR EMBL; LATX01000271; KTB46719.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0W0GDW3; -.
DR eggNOG; KOG0903; Eukaryota.
DR Proteomes; UP000054988; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0046854; P:phosphatidylinositol phosphate biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05168; PI4Kc_III_beta; 1.
DR Gene3D; 1.10.1070.11; Phosphatidylinositol 3-/4-kinase, catalytic domain; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR InterPro; IPR036940; PI3/4_kinase_cat_sf.
DR InterPro; IPR018936; PI3/4_kinase_CS.
DR InterPro; IPR015433; PI_Kinase.
DR PANTHER; PTHR10048:SF22; PHOSPHATIDYLINOSITOL 4-KINASE BETA; 1.
DR PANTHER; PTHR10048; PHOSPHATIDYLINOSITOL KINASE; 1.
DR Pfam; PF00454; PI3_PI4_kinase; 1.
DR SMART; SM00146; PI3Kc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00916; PI3_4_KINASE_2; 1.
DR PROSITE; PS50290; PI3_4_KINASE_3; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Reference proteome {ECO:0000313|Proteomes:UP000054988};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..1048
FT /note="PI3K/PI4K catalytic domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006902601"
FT DOMAIN 745..1033
FT /note="PI3K/PI4K catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50290"
FT REGION 189..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 456..479
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 562..604
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 657..678
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..479
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 562..594
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 657..673
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1048 AA; 117771 MW; BA01FC3444985838 CRC64;
MSHALLLRLF LTPFFSVHVA LQYLQTYPDN IGITYYITRR LRELDISELR DVWGFICHLL
LTRPSKSRAL ECFVVDVSQR STHIALFTLW FMQAALKDLP SIHHESVTFS ICQRVLHKCH
EIIFSDLPPA ASPYATLSLP FRSRFSRKKV KHHTEPAIIG IGMVLAGTPA LPRLTDIMGE
VAIEQGRVEE TTEMRSIESQ ADDLATGSKL EAEDSQEDEE NDLPATENNQ NLQKGGSDEP
QRLMRRRSTI GPSQTVPALP LHLQNFRRSR NSEDPLGQLD AEPIAGQVTT PYQSSPSIPS
TRPMITRMSS QNPDTILQTY DLQSQLHLLK SHYCRSEVQF ILTLENIANR LLVVPRPARV
SALRAELTSL NHKLPAEICM PMWCTSSDTL QKTSHTTQPH HRIVRIPPGE CVVLNSAEKA
PYLLYIEVVN DDLDFDPQKR SNKDVLKKIV VREDESRGTS REMNPFSTFV PTPLQQSGTA
DTDADLAFEE RPTSIDKALV ITPPTPSTAD STPIDAEEEM DLVDQLYGVD QSLRSRTIDL
SESIVLPPAP KNKDLDMVAW SRPSSIPSTP NVEADNRASL IPESSRSSPA PHRDTSNSTH
HDTISLDEYS ERMRTAAIML AQLNANLSRE PIVIPSDAQS SGPLSWITGS NWLTISSDSS
KNSSPNPSGS QDFGKPMVSR MRLQPADAYA IRDRIMQEML ALEEERMARM RETREGESSI
RMGDIGDGLK TAEDESIIRK ELSKADPSAM VFSESWTTKK SRIRHGSPYG HLANWDCVSV
IVKTGGDLRQ EQLAVQLIRE FQQIWEEENC QCWVRPFRIL ITGGSSGLVE TITDAVSIHS
IKKSEYARRL AEGRLGHVTL LDHFKSTYGD PSSAKFARAR RNFAKSLAGY SIVTYLLQIK
DRHNGNILLD RNGHLIHIDF GFMLSNTPGN IRFEAAPFKL PPEYVEVLGG VDGLSFLEFK
QLFREGFEAA RKHCDRIITL VELMQKDSTL PCFVAFGEQT ATQLRDRFQP ALTHSLVGEL
VDRLIYSSLG SHWTRLYDSY QYYSQSIL
//
