ID A0A0W0R236_9GAMM Unreviewed; 675 AA.
AC A0A0W0R236;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN Name=arcB_3 {ECO:0000313|EMBL:VEH85427.1};
GN ORFNames=Lade_1577 {ECO:0000313|EMBL:KTC65054.1}, NCTC12735_01057
GN {ECO:0000313|EMBL:VEH85427.1};
OS Legionella adelaidensis.
OG Plasmid 13 {ECO:0000313|EMBL:VEH85427.1,
OG ECO:0000313|Proteomes:UP000281170}.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=45056 {ECO:0000313|EMBL:KTC65054.1, ECO:0000313|Proteomes:UP000054859};
RN [1] {ECO:0000313|EMBL:KTC65054.1, ECO:0000313|Proteomes:UP000054859}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1762-AUS-E {ECO:0000313|EMBL:KTC65054.1,
RC ECO:0000313|Proteomes:UP000054859};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Identification of large and diverse effector repertoires of 38 Legionella
RT species.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:VEH85427.1, ECO:0000313|Proteomes:UP000281170}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC12735 {ECO:0000313|EMBL:VEH85427.1,
RC ECO:0000313|Proteomes:UP000281170};
RC PLASMID=13 {ECO:0000313|Proteomes:UP000281170};
RG Pathogen Informatics;
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; LNKA01000010; KTC65054.1; -; Genomic_DNA.
DR EMBL; LR134422; VEH85427.1; -; Genomic_DNA.
DR RefSeq; WP_058462656.1; NZ_LR134422.1.
DR AlphaFoldDB; A0A0W0R236; -.
DR STRING; 45056.Lade_1577; -.
DR KEGG; ladl:NCTC12735_01057; -.
DR PATRIC; fig|45056.6.peg.1627; -.
DR OrthoDB; 9810730at2; -.
DR Proteomes; UP000054859; Unassembled WGS sequence.
DR Proteomes; UP000281170; Plasmid 13.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43047:SF72; OSMOSENSING HISTIDINE PROTEIN KINASE SLN1; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:KTC65054.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Plasmid {ECO:0000313|EMBL:VEH85427.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054859};
KW Transferase {ECO:0000313|EMBL:VEH85427.1}.
FT DOMAIN 219..271
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 282..504
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 551..670
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 600
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 675 AA; 75843 MW; FA5157FEDA061070 CRC64;
MKSIEEDKIT TFGEAYTLLG ISLIVIDKQL NIKYINDFCK KLLGIQKSKV INTSIIPFWK
SLGLPSLINS NAKLIGKPIR IGRHYKKWAK KKILIDNIPH YFLVDEDVTE IEAIKHAVSS
ECAKVTGHRF NNKLSTVEYI HEIYNYLTNI INKIPCYIYW KNTKLEYIGC NQLAADFVHF
DSPQEIIGKT DLDIFIDRKL AKSYQKVDKI ILRTGKSILN EPGLLVNEDH KTLHTLVSKV
PIHDIRGKII GLVGITVDIT ELMEAKDSAE AASRAKSEFI ANMSHDIRTP LTGIIGMSHI
LEEEVHNPEE RQHAHWVNVS GEKLLGLLNG VLDMVATDSA NENELKHETF DLYQVVKDVL
ELQSAAVKTR QLDIKSHIEE AVPRFIIGDK MKLHRILLNL IGNAIKFTEK GHVGIDAKVK
SMKNGVAHIE FLVFDTGIGI PEEFLDKVFD RFFKVSPSYK GIYTGNGIGL HIVRKYIELL
KGTISLTSKE GVGTTFSVVL PMEIDKRPRS DFLTNTSISQ VTEQVSLTCK EDSLPPSSNV
ITESVKLEMI QILLVEDNFI ALTVLKNMVE GLPAQVFVAD DAEKAFSLVQ SQLFDLIITD
IGLPGKSGDE LAKEIRRWEE KNNKEPTPII GLTGHNAQEI SQICLEAGIN QIYSKPMQLE
ILQNIIKTYV KTSIT
//
