ID A0A0W0R6L2_9GAMM Unreviewed; 364 AA.
AC A0A0W0R6L2;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Aminoglycoside N (6')-acetyltransferase {ECO:0000313|EMBL:KTC66661.1};
GN Name=aacA4 {ECO:0000313|EMBL:KTC66661.1};
GN Synonyms=aacA {ECO:0000313|EMBL:VEH85836.1};
GN ORFNames=Lade_1319 {ECO:0000313|EMBL:KTC66661.1}, NCTC12735_01475
GN {ECO:0000313|EMBL:VEH85836.1};
OS Legionella adelaidensis.
OG Plasmid 24 {ECO:0000313|EMBL:VEH85836.1,
OG ECO:0000313|Proteomes:UP000281170}.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=45056 {ECO:0000313|EMBL:KTC66661.1, ECO:0000313|Proteomes:UP000054859};
RN [1] {ECO:0000313|EMBL:KTC66661.1, ECO:0000313|Proteomes:UP000054859}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1762-AUS-E {ECO:0000313|EMBL:KTC66661.1,
RC ECO:0000313|Proteomes:UP000054859};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Identification of large and diverse effector repertoires of 38 Legionella
RT species.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:VEH85836.1, ECO:0000313|Proteomes:UP000281170}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC12735 {ECO:0000313|EMBL:VEH85836.1,
RC ECO:0000313|Proteomes:UP000281170};
RC PLASMID=24 {ECO:0000313|Proteomes:UP000281170};
RG Pathogen Informatics;
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LNKA01000001; KTC66661.1; -; Genomic_DNA.
DR EMBL; LR134433; VEH85836.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0W0R6L2; -.
DR STRING; 45056.Lade_1319; -.
DR KEGG; ladl:NCTC12735_01475; -.
DR PATRIC; fig|45056.6.peg.1363; -.
DR Proteomes; UP000054859; Unassembled WGS sequence.
DR Proteomes; UP000281170; Plasmid 24.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR CDD; cd04301; NAT_SF; 1.
DR Gene3D; 3.40.630.30; -; 2.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR000182; GNAT_dom.
DR PANTHER; PTHR31438; LYSINE N-ACYLTRANSFERASE C17G9.06C-RELATED; 1.
DR PANTHER; PTHR31438:SF1; LYSINE N-ACYLTRANSFERASE C17G9.06C-RELATED; 1.
DR Pfam; PF00583; Acetyltransf_1; 1.
DR Pfam; PF13523; Acetyltransf_8; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 2.
DR PROSITE; PS51186; GNAT; 2.
PE 4: Predicted;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW Plasmid {ECO:0000313|EMBL:VEH85836.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054859};
KW Transferase {ECO:0000313|EMBL:KTC66661.1}.
FT DOMAIN 3..185
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
FT DOMAIN 187..343
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
SQ SEQUENCE 364 AA; 41901 MW; 5F4A1D8F86769313 CRC64;
MSIQFEKAEI NHIDIIFSWL AEPFVQEFWD NTQGHKDDIL NFVNGRTEPS NYCDGKYVYW
IASCDGHPFA MLMTIQETAE DHIDDIKLNH LSKTGHTYGI DYMIGDKNFF GKGYGAKTLL
EFLNFFRREF DVLADTFLID PAIDNVRAKH VYMKAGFEHI ADFVMGGGCS GAGKVHHLLI
KRFAPAIRLL PATIADYPTI QNMARFYVYD RTAYMGWECP ESGLFECIDF KHYFENPDEQ
AFLIRVSDEI AGFVLLDKMH LLESVDWNMG EFFVLAKFQG KGVASIVAQE IFKEHPGKWS
IAVMPENIKA VKFWRKIIAQ ATHNYYREVF KTADELRSTK NPDPYAMNVF TFDINDQMFV
GDIA
//
