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Database: UniProt
Entry: A0A0W0S033_9GAMM
LinkDB: A0A0W0S033_9GAMM
Original site: A0A0W0S033_9GAMM 
ID   A0A0W0S033_9GAMM        Unreviewed;       746 AA.
AC   A0A0W0S033;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   12-AUG-2020, entry version 15.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   Name=feoB {ECO:0000313|EMBL:KTC76831.1};
GN   ORFNames=Lbru_2938 {ECO:0000313|EMBL:KTC76831.1};
OS   Legionella brunensis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales;
OC   Legionellaceae; Legionella.
OX   NCBI_TaxID=29422 {ECO:0000313|EMBL:KTC76831.1, ECO:0000313|Proteomes:UP000054742};
RN   [1] {ECO:0000313|EMBL:KTC76831.1, ECO:0000313|Proteomes:UP000054742}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43878 {ECO:0000313|EMBL:KTC76831.1,
RC   ECO:0000313|Proteomes:UP000054742};
RA   Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA   Pupko T., Shuman H.A., Segal G.;
RT   "Genomic analysis of 38 Legionella species identifies large and diverse
RT   effector repertoires.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake system.
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|RuleBase:RU362098}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC       GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KTC76831.1}.
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DR   EMBL; LNXV01000036; KTC76831.1; -; Genomic_DNA.
DR   RefSeq; WP_058442901.1; NZ_LNXV01000036.1.
DR   EnsemblBacteria; KTC76831; KTC76831; Lbru_2938.
DR   PATRIC; fig|29422.6.peg.3114; -.
DR   OrthoDB; 304844at2; -.
DR   Proteomes; UP000054742; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR006073; GTP_binding_domain.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|ARBA:ARBA00022496,
KW   ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM        273..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        315..335
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        342..365
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        385..405
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        412..438
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        444..464
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        654..675
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        682..702
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        714..732
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   DOMAIN          1..166
FT                   /note="FeoB-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51711"
SQ   SEQUENCE   746 AA;  81929 MW;  0FDB0D77228E1C78 CRC64;
     MTHILLVGNP NCGKTTLFNA LTGANQRVGN WPGVTVEKKT GSYSLKETVI QVTDLPGVYS
     LSSSTTSSQD EQIAASALVT LDADIIINVI DACHLERHLY LTSQILELGK PVILVLNMMD
     IASQRGIKID IQALAKQLQC PVLPMQAHKK IGIDVLNQVI CENPKPANAL ELQFSQGIKD
     VLQDLEQQLS KVGVVRQLRS YYARRILEGD NHLLNSNEDI ACVMEEKGQE LDILLADARY
     QKIHEFVLNV QKKESDTSEH FTAKLDRLVL HRYFALPIFL TMMYLMFLFA INIGGAFQDF
     FDITTDTLFV QGSAWVLQQL HMPNWLIALV ANGIGKGINT TLTFIPVIAA MFFFLSLLEA
     SGYMARAAFV VDKIMRALGL PGKSFVPMIV GFGCNVPAIM AARTLDSERD RLLTVMMSPF
     MSCSARLAIY AVFVAAFFPT GGQNVVFSLY LMGILMAVLT GFVLRKTTLR GQASPLILEL
     PAYHKPALKR LLKETSLRLR HFVIRAGRLI IPVCVILGGL NALTVEGGIS SGEANTHSVL
     SLLGQWLTPI FAPMGLHQDN WPATVGLLTG MLAKEVVVGS LNTLYAQLGH LGQISAASFD
     FWGSLQTALW SIPQNLSELG QALLNPLVAS APDNEVSQSV YGMMVERFDG KAGAYAYLVF
     ILLYIPCVST MAVIRQEASS KLMWFSIIWS FVVAYLSAVL VYQLATFTSH PQQSLAWVLI
     ITSAVIISWG VLRQLSSGDE YVTANT
//
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