ID A0A0W0SLF8_9GAMM Unreviewed; 369 AA.
AC A0A0W0SLF8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Naringenin-chalcone synthase {ECO:0000313|EMBL:KTC84198.1};
DE EC=2.3.1.74 {ECO:0000313|EMBL:KTC84198.1};
GN ORFNames=Lbru_1559 {ECO:0000313|EMBL:KTC84198.1};
OS Legionella brunensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=29422 {ECO:0000313|EMBL:KTC84198.1, ECO:0000313|Proteomes:UP000054742};
RN [1] {ECO:0000313|EMBL:KTC84198.1, ECO:0000313|Proteomes:UP000054742}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43878 {ECO:0000313|EMBL:KTC84198.1,
RC ECO:0000313|Proteomes:UP000054742};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Genomic analysis of 38 Legionella species identifies large and diverse
RT effector repertoires.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTC84198.1}.
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DR EMBL; LNXV01000011; KTC84198.1; -; Genomic_DNA.
DR RefSeq; WP_058441624.1; NZ_LNXV01000011.1.
DR AlphaFoldDB; A0A0W0SLF8; -.
DR STRING; 29422.Lbru_1559; -.
DR PATRIC; fig|29422.6.peg.1649; -.
DR OrthoDB; 9786288at2; -.
DR Proteomes; UP000054742; Unassembled WGS sequence.
DR GO; GO:0102128; F:chalcone synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0016210; F:naringenin-chalcone synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR PANTHER; PTHR11877:SF46; TYPE III POLYKETIDE SYNTHASE A; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:KTC84198.1};
KW Transferase {ECO:0000313|EMBL:KTC84198.1}.
FT DOMAIN 5..212
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 229..365
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 154
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 369 AA; 41156 MW; D0AC97B792607CA5 CRC64;
MQPAITAIGV ATPPYKRSQQ EIAELICEGL KLRPAEKRFL KAIYKASGIQ QRHSVLSDYC
KSQGEFDFFP NQPDEQLPTT AKRMQIYKQH ALILALQAIE NCLEGLTTFS KKEITHLITV
SCTGMYAPGL DIEIVQRLEL LPSTKRTAIN FMGCYGAFNG MRIADTICQA APDSNVLVVC
IELCTIHFQK AQTTENIISN AIFADGAAAV LIQGKQNNSI YLTLESFHCD LVPQTNQEMA
WHIADSGFDI VLSSYVPDVI KSGIAAFAKN LLNKKNWSFN DIDYYAIHPG GFKILQACES
ALNITPEDNQ YSYEVLNQFG NMSSATVLFV LKRIWNSLKK QDHKKNIFSC AFGPGLTLES
MLLKTHCMF
//
