ID A0A0W0SSQ4_9GAMM Unreviewed; 415 AA.
AC A0A0W0SSQ4;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Acriflavin resistance protein E {ECO:0000313|EMBL:KTC86307.1};
GN Name=acrA {ECO:0000313|EMBL:KTC86307.1};
GN ORFNames=Lbru_0801 {ECO:0000313|EMBL:KTC86307.1};
OS Legionella brunensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=29422 {ECO:0000313|EMBL:KTC86307.1, ECO:0000313|Proteomes:UP000054742};
RN [1] {ECO:0000313|EMBL:KTC86307.1, ECO:0000313|Proteomes:UP000054742}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43878 {ECO:0000313|EMBL:KTC86307.1,
RC ECO:0000313|Proteomes:UP000054742};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Genomic analysis of 38 Legionella species identifies large and diverse
RT effector repertoires.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTC86307.1}.
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DR EMBL; LNXV01000005; KTC86307.1; -; Genomic_DNA.
DR RefSeq; WP_058440901.1; NZ_LNXV01000005.1.
DR AlphaFoldDB; A0A0W0SSQ4; -.
DR STRING; 29422.Lbru_0801; -.
DR PATRIC; fig|29422.6.peg.835; -.
DR OrthoDB; 9806939at2; -.
DR Proteomes; UP000054742; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF11; BLL4320 PROTEIN; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 70..259
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 140..167
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 415 AA; 45626 MW; B59BFE7CD1EFA855 CRC64;
MKKRMTIMII ALGVVFGGII AFNLFKSFMI KRFFATYEPP AVTVSSVTAV KKNWEPRISA
VGNFMAINGV DVNSQAAGNV VKIHFESGQY LEKDQPLIDI DDSVDQATLK FNKADLALKQ
LSYQRQADLF KRGATSSSNV DEATANLQQA QANVEKTQAE IRQKHILAPF SGRLGIRQVN
LGQYITPGQT SIVTLQSMDP LFLEFYLPEQ MLKRLHINQE IQFSVEGIPH TLFEGKITAL
NAKVDTNTHN ILVQATVPNC PTTKDSKLVT VNKQKDGEKM LVTCDSNLNA KNKLSQFAFI
PGMFASISVE QPAVPNVVVL PSTAISYSLY GNSVFVIEKD KDGKKDSEGK DILRVKRVFV
STGEQEGNFT VIKKGVEAGQ QVVSSGELKL QNGTRVVINN SVELNNVANP DQLGE
//
