ID A0A0W0SSQ8_9GAMM Unreviewed; 1029 AA.
AC A0A0W0SSQ8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Multidrug efflux transporter {ECO:0000313|EMBL:KTC86308.1};
GN ORFNames=Lbru_0802 {ECO:0000313|EMBL:KTC86308.1};
OS Legionella brunensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=29422 {ECO:0000313|EMBL:KTC86308.1, ECO:0000313|Proteomes:UP000054742};
RN [1] {ECO:0000313|EMBL:KTC86308.1, ECO:0000313|Proteomes:UP000054742}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43878 {ECO:0000313|EMBL:KTC86308.1,
RC ECO:0000313|Proteomes:UP000054742};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Genomic analysis of 38 Legionella species identifies large and diverse
RT effector repertoires.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTC86308.1}.
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DR EMBL; LNXV01000005; KTC86308.1; -; Genomic_DNA.
DR RefSeq; WP_058440902.1; NZ_LNXV01000005.1.
DR AlphaFoldDB; A0A0W0SSQ8; -.
DR STRING; 29422.Lbru_0802; -.
DR PATRIC; fig|29422.6.peg.836; -.
DR OrthoDB; 9758297at2; -.
DR Proteomes; UP000054742; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF28; BLR2861 PROTEIN; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 430..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..481
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 521..542
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 843..863
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 870..890
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 896..920
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 941..962
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 974..1000
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1029 AA; 112501 MW; 7A18DF27A80A073C CRC64;
MKFTDIFIKR PVLATVVSLL IFLFGLNSIL TMQIRQYPRM DNTVITITTA YPGADADLIA
GFITTPLEAA VASAEGIDYM TSSSTQGLST ITLTIKLNFD PQVAFTDVMS KVQQVINQLP
PEAQQPVIVK SSDTATPLMY ISLDSTDMTP QQITDYATRV VQPQLQTVDG VAKAEILGGA
TYSMRIFLDP IKMAALNVSP ADVSNVLARN NFLTAAGNTK GEYVAINMTA KTDLNNAEEF
SQLIVRSNKN SIIRLRDIAK IELGSQDYNT SVRFDGKKAV FLAITPTPTA NPLTVINDAR
KMMPSIQREF PPSLKGTIVY DATDFIRASI EEVVQTILEA ALIVIVVIFL FLGSIRSVII
PVVTIPLSLI GVCTFMLFLG YSINLLTLLA FVLAIGLVVD DAIVVVENVH RHIEEGRTPL
QAAIVGAREI ATPVIAMTIT LAAVYAPIGF MGGLTGALFK EFAFTLASAV VISGIIALTL
TPMMCSKILT SDISSGRFVH FLDDKFNKLK IRYQRTLHSL LNTRSIMLVF AAVVLLVLPY
LYTHTPEETA PEEDQGFFFV VGTAPQYATI NYIEAFTKPF DAIYKSFPET EHYFTVNMSA
PVSGMVLKAW DRRDRTQFQL KEPLQQKLDE VAGLKSFAVI PPPLPGGGSG TPIQFVIKTT
NDFQTLFDVS NKLLEKAQKS GLFIYLDNSL KFNQPEMEFQ INRSKASDLG LDMQAIGSSL
TSALSGNYVN YFNLQGRSYQ VIPQLDRKYR LTPEQLGKIY VRTADGAMVP LSTVVTAKEK
VQPNAVSHFQ QLNSATIQGV MMPGTTLGQG LTFLAEQAKD VLPKGFTFDY GGQSRQFVQE
GSALILAFFL AIIVIFLVLS AQYESFRDPL IILISVPMSI CGALIPLNLG AASINIYTQV
GLITLIGLIS KHGILIVDFA NQLQREKQLD RRAAVEEAAG IRLRPILMTT AAMVFGVIPL
LVATGAGAVS RFDIGLVIAM GLLVGTSFTL FVVPTMYTYL AADHRHDLEK EKKATISQDS
SEFNPPKSE
//
