ID A0A0W0TNH7_9GAMM Unreviewed; 417 AA.
AC A0A0W0TNH7;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Tol-Pal system protein TolB {ECO:0000256|HAMAP-Rule:MF_00671};
DE Flags: Precursor;
GN Name=tolB {ECO:0000256|HAMAP-Rule:MF_00671,
GN ECO:0000313|EMBL:KTC97135.1};
GN ORFNames=E4T54_01320 {ECO:0000313|EMBL:QBS11489.1}, Lgee_2106
GN {ECO:0000313|EMBL:KTC97135.1};
OS Legionella geestiana.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=45065 {ECO:0000313|EMBL:KTC97135.1, ECO:0000313|Proteomes:UP000054785};
RN [1] {ECO:0000313|EMBL:KTC97135.1, ECO:0000313|Proteomes:UP000054785}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49504 {ECO:0000313|EMBL:KTC97135.1,
RC ECO:0000313|Proteomes:UP000054785};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Genomic analysis of 38 Legionella species identifies large and diverse
RT effector repertoires.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:QBS11489.1, ECO:0000313|Proteomes:UP000294523}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1308 {ECO:0000313|EMBL:QBS11489.1,
RC ECO:0000313|Proteomes:UP000294523};
RA Durieux I., Ginevra C., Attaiech L., Picq K., Juan P.A., Jarraud S.,
RA Charpentier X.;
RT "Diverse conjugative elements silence natural transformation in Legionella
RT species.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC membrane invagination during cell division and is important for
CC maintaining outer membrane integrity. {ECO:0000256|HAMAP-
CC Rule:MF_00671}.
CC -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC TolB and the outer membrane protein Pal. They form a network linking
CC the inner and outer membranes and the peptidoglycan layer.
CC {ECO:0000256|HAMAP-Rule:MF_00671}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|ARBA:ARBA00004418,
CC ECO:0000256|HAMAP-Rule:MF_00671}.
CC -!- SIMILARITY: Belongs to the TolB family. {ECO:0000256|ARBA:ARBA00009820,
CC ECO:0000256|HAMAP-Rule:MF_00671}.
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DR EMBL; LNYC01000073; KTC97135.1; -; Genomic_DNA.
DR EMBL; CP038271; QBS11489.1; -; Genomic_DNA.
DR RefSeq; WP_051550848.1; NZ_UGNZ01000001.1.
DR AlphaFoldDB; A0A0W0TNH7; -.
DR STRING; 45065.Lgee_2106; -.
DR KEGG; lgt:E4T54_01320; -.
DR PATRIC; fig|45065.4.peg.2286; -.
DR OrthoDB; 9802240at2; -.
DR Proteomes; UP000054785; Unassembled WGS sequence.
DR Proteomes; UP000294523; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0017038; P:protein import; IEA:InterPro.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR Gene3D; 3.40.50.10070; TolB, N-terminal domain; 1.
DR HAMAP; MF_00671; TolB; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR011659; PD40.
DR InterPro; IPR014167; Tol-Pal_TolB.
DR InterPro; IPR007195; TolB_N.
DR NCBIfam; TIGR02800; propeller_TolB; 1.
DR PANTHER; PTHR36842; PROTEIN TOLB HOMOLOG; 1.
DR PANTHER; PTHR36842:SF1; TOL-PAL SYSTEM PROTEIN TOLB; 1.
DR Pfam; PF07676; PD40; 3.
DR Pfam; PF04052; TolB_N; 1.
DR SUPFAM; SSF52964; TolB, N-terminal domain; 1.
DR SUPFAM; SSF69304; Tricorn protease N-terminal domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|HAMAP-Rule:MF_00671};
KW Cell division {ECO:0000256|HAMAP-Rule:MF_00671};
KW Periplasm {ECO:0000256|ARBA:ARBA00022764, ECO:0000256|HAMAP-Rule:MF_00671};
KW Reference proteome {ECO:0000313|Proteomes:UP000054785};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|HAMAP-Rule:MF_00671}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00671"
FT CHAIN 20..417
FT /note="Tol-Pal system protein TolB"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00671"
FT /id="PRO_5034528909"
FT DOMAIN 20..111
FT /note="TolB N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04052"
SQ SEQUENCE 417 AA; 45339 MW; 88EDEF278F656CEA CRC64;
MRKSIATLVF VCLSQWAFAL DLELTQGTVA AYPIGVQNFA NSNSAELEDI VRNDLHFSGQ
FRLIPEPAGS GGAIPSWRSA GADSVLKGSV TPIGANRFDV RFELLDAAAQ GRLLLAKNYQ
VGRADLRALA HHISDEVYQK LTGERGVFST RIAYVLVQRS GERSRYSLEV ADVDGYGPQS
LLISSEPIMS PSWSPDGRQI ACVSFERKRA QIFIIDVASG RRRLVTDFPG INGAPAWSPD
GRELAVVLSK TGSPKIYTVN LANGQMTQRT FGDSIDTEPR YSPDGQSLIF TSGRGGSPQV
YQLSLAGGTV SRLTYEGNYN ARASWTPNKR YLVMLHREDS GFQIAAQEMP GGRVLSLTSS
GLDESPSVAP NSRLVLYATR FHDKGVLSMV SIDGGIQMRL PSRDGDVQEP AWSPYLG
//
