ID A0A0W0TS10_9GAMM Unreviewed; 385 AA.
AC A0A0W0TS10;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
DE AltName: Full=DNA 3'-5' helicase II {ECO:0000256|ARBA:ARBA00034923};
GN ORFNames=Lfee_1518 {ECO:0000313|EMBL:KTC98413.1};
OS Legionella feeleii.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=453 {ECO:0000313|EMBL:KTC98413.1, ECO:0000313|Proteomes:UP000054698};
RN [1] {ECO:0000313|EMBL:KTC98413.1, ECO:0000313|Proteomes:UP000054698}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WO-44C {ECO:0000313|EMBL:KTC98413.1,
RC ECO:0000313|Proteomes:UP000054698};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Genomic analysis of 38 Legionella species identifies large and diverse
RT effector repertoires.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTC98413.1}.
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DR EMBL; LNYB01000069; KTC98413.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0W0TS10; -.
DR STRING; 453.Lfee_1518; -.
DR PATRIC; fig|453.4.peg.1665; -.
DR Proteomes; UP000054698; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KTC98413.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054698}.
FT DOMAIN 2..52
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|Pfam:PF00580"
FT DOMAIN 170..350
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13361"
SQ SEQUENCE 385 AA; 45118 MW; A2484FBD70D269D4 CRC64;
MVLIDEFQDF NKLEVELVNV LEARNKLVIV GDDDQAIYSF RGANPQYLRE KYHSDKYINF
TLPFCCRCTQ VIVDAVNTIV EKANVKERIA KEYRCYLPEK KEDSIAYKKI MHKHFTVQGR
QRTTNYMGKF ISHFYKRIEA SEKENARRQR KTLILIIGPR HYLDQIYPLL VEEVGEENIS
YRKSKQAKKL IVALKLIKAD RNSNLGWRLI AEEKLSSSEL NALIKQSISD NFLEIIPSEL
EKTVTNVLIL LDQKEYHQEA VQEFLKLHEI SQIEMLWDTQ DQNKLFEDDE YSQIKLATFE
GSKGLAADYV FITGLQEGVL PKTNNATEAE ICKFIVALTR TRKQCYIFTC GRFSGTLQKK
SFFLNWISEY LFYEKIDKSK INDYQ
//
