ID A0A0W0V2G8_9GAMM Unreviewed; 787 AA.
AC A0A0W0V2G8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Inner membrane protein/sensory box protein LssE {ECO:0000313|EMBL:KTD14286.1};
GN ORFNames=Lisr_2514 {ECO:0000313|EMBL:KTD14286.1};
OS Legionella israelensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=454 {ECO:0000313|EMBL:KTD14286.1, ECO:0000313|Proteomes:UP000054761};
RN [1] {ECO:0000313|EMBL:KTD14286.1, ECO:0000313|Proteomes:UP000054761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bercovier 4 {ECO:0000313|EMBL:KTD14286.1,
RC ECO:0000313|Proteomes:UP000054761};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Genomic analysis of 38 Legionella species identifies large and diverse
RT effector repertoires.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTD14286.1}.
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DR EMBL; LNYH01000149; KTD14286.1; -; Genomic_DNA.
DR RefSeq; WP_058502798.1; NZ_UGOE01000001.1.
DR AlphaFoldDB; A0A0W0V2G8; -.
DR STRING; 454.Lisr_2514; -.
DR PATRIC; fig|454.4.peg.2750; -.
DR OrthoDB; 9787514at2; -.
DR Proteomes; UP000054761; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR031621; HisKA_7TM.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR33121:SF23; CYCLIC DI-GMP PHOSPHODIESTERASE PDEB; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF16927; HisKA_7TM; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054761};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 38..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 68..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 152..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 249..302
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 401..534
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 545..787
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 787 AA; 91577 MW; 74DF0796142EE692 CRC64;
MLPLNHFKFS IFGLSNLLVA CAVLLLGLVS LFRTRFSFLA ITLFLLTFTI SSWLLSFIFL
YISKSEALAF WWANVGYLFV PVISPAAYLF IASFLGIVNQ RKFYLILFFS LGVFFTISQF
YFHAIFSELY QYQWGYYPKF EWRFYPKFNS GFSLIFLFFF FSVMILCFVE LWNEYKKIRH
THKMQKIKQI KLVGFAFLTG YIGSIDFIPC FGIDIYPLGV MFIGFFIAIL CYVIEKYHLL
DSPTFVANQI IETINDALIV CDHEGLIRIA NPAVISLSQY RQEELIDRSI NSLLLIHSYD
NEHENFFQLI VNEKFIQGLE ISMARKNNSD IPVAISCSHI VGINNKTKGW VIVVRDISEI
KKNIAQLIYL SSHDYLTGIY NRKKFEDELA YHIRLSNRTH QCNAFLLLDI DHFKEINDNF
GHQHGDKLLI CFADFLKKYF RQTDVVGRFG GDEFAVIVTN IQPQDINELA TQLIKTIRNF
PFSVNGQTIT VTVSIGIALF PKANEDKLDL LMHADLALYQ CKVKNRNAYE IYDPSVNWNF
LFKNKVQLAN MIKEAMNEGR LILFSQPIFN VHQDKVSHYE LLLRMKNKDK IILPENFLDV
AEHYGLMREI NLFVIKTTIA LLEKYHDLYL TCNISSNALN DEQIYHVLIE SIKEKKFAPE
RLILEINEHI VVTHIKSAIN FMKSCRNLGV KFALDDFGVG LSSFTHLKYM PVDFLKIDGS
FIKNILKNEI DRQFVKSMVE IAKTLKIKTI AEYVEDEETV HLLRQLGVDY AQGFYFGRPE
YKFKLID
//
