ID A0A0W0VHP6_9GAMM Unreviewed; 655 AA.
AC A0A0W0VHP6;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=ATP dependent DNA helicase (DEAD box family) Rad3 {ECO:0000313|EMBL:KTD19626.1};
GN ORFNames=Lisr_1912 {ECO:0000313|EMBL:KTD19626.1};
OS Legionella israelensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=454 {ECO:0000313|EMBL:KTD19626.1, ECO:0000313|Proteomes:UP000054761};
RN [1] {ECO:0000313|EMBL:KTD19626.1, ECO:0000313|Proteomes:UP000054761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bercovier 4 {ECO:0000313|EMBL:KTD19626.1,
RC ECO:0000313|Proteomes:UP000054761};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Genomic analysis of 38 Legionella species identifies large and diverse
RT effector repertoires.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the helicase family. DinG subfamily.
CC {ECO:0000256|ARBA:ARBA00038058}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTD19626.1}.
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DR EMBL; LNYH01000110; KTD19626.1; -; Genomic_DNA.
DR RefSeq; WP_058502237.1; NZ_UGOE01000001.1.
DR AlphaFoldDB; A0A0W0VHP6; -.
DR STRING; 454.Lisr_1912; -.
DR PATRIC; fig|454.4.peg.2084; -.
DR OrthoDB; 9805194at2; -.
DR Proteomes; UP000054761; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006555; ATP-dep_Helicase_C.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR045028; DinG/Rad3-like.
DR InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR PANTHER; PTHR11472:SF47; FANCONI ANEMIA GROUP J PROTEIN; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF13307; Helicase_C_2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00491; HELICc2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:KTD19626.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054761}.
FT DOMAIN 20..281
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51193"
SQ SEQUENCE 655 AA; 73834 MW; 7E8C2955A1151D13 CRC64;
MEINTDLVQS CRRILSDKGR LSTALPGFVS RTAQSELAAA IAQTIEQHSV LVAEAGTGTG
KTFAYLIPGL LSGKKVLIST ATKTLQDQLF QKDLPMLVKA LGLSVRMQNL KGRANYICRY
RVALYSAEAS FQNPQCIHDI LHVKEKLPQL KEGDRSELPE LKEDSKAWPY VTSTTENCLG
SECPQHSECF LMKARKRAMD ADIVVINHHL FFADSRLKKQ GFAELLPGFD VVIFDEAHQL
PDVATGFYGE RVGTRQFREL MDDVLKEWPV LDLANQPLKQ LSLQAERMFD QMLSVLSTRE
ERVSWQKIRS HHGFMALWED WLTLKNELSI CLQDEQVKEI TGIKRCRERL EAIEKVLSSF
ENEDSHCIRW LERFKHTLVF HSTPYEIANE FGQLLKRQNS AYIFTSATLT MAGAFDSFTK
PLGLGDVETL SLPSPFNFRQ QALLYLPRTL PDPKDGRYHD LLLQKVLPVI DALGGRCFFL
FTSHRALKQV AQRMANHLKY PLLVQGDEAK PILLARFRQL GNAVLLGTAT FWEGVDVKGE
ALSCVIIDKL PFASPVDPVV QGKMAYLKAR GLSAFDELSL PSAVIALKQG VGRLIRDVED
KGLLIIADPR LTGREYGRLI LASLPKLPVT RDEEKVFSFI NELALKDLKN ECISY
//
