ID A0A0W0VND6_9GAMM Unreviewed; 433 AA.
AC A0A0W0VND6;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Voltage-gated chloride channel protein (ClC-type) {ECO:0000313|EMBL:KTD21636.1};
GN Name=clcA {ECO:0000313|EMBL:KTD21636.1};
GN ORFNames=Llon_0801 {ECO:0000313|EMBL:KTD21636.1};
OS Legionella londiniensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=45068 {ECO:0000313|EMBL:KTD21636.1, ECO:0000313|Proteomes:UP000054997};
RN [1] {ECO:0000313|EMBL:KTD21636.1, ECO:0000313|Proteomes:UP000054997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49505 {ECO:0000313|EMBL:KTD21636.1,
RC ECO:0000313|Proteomes:UP000054997};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Genomic analysis of 38 Legionella species identifies large and diverse
RT effector repertoires.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTD21636.1}.
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DR EMBL; LNYK01000014; KTD21636.1; -; Genomic_DNA.
DR RefSeq; WP_058529090.1; NZ_UGON01000002.1.
DR AlphaFoldDB; A0A0W0VND6; -.
DR STRING; 45068.Llon_0801; -.
DR PATRIC; fig|45068.5.peg.853; -.
DR OrthoDB; 9767361at2; -.
DR Proteomes; UP000054997; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd01031; EriC; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR45711; CHLORIDE CHANNEL PROTEIN; 1.
DR PANTHER; PTHR45711:SF6; CHLORIDE CHANNEL PROTEIN; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
PE 4: Predicted;
KW Chloride {ECO:0000256|ARBA:ARBA00023214};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054997};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 48..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 148..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 293..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 433 AA; 47033 MW; 8C7A3D985F22D96C CRC64;
MRDKILVLYA LSIVLGAVTG FVGAYLQISI HLMNKLLVNW FAYAESKNWP VGLVSALTSM
FMVFIAWAMV KWIAAEASGS GVQEIEGTLL HERPIFWRRL LPVKFIGGVL AISAKMVLGR
EGPTIQIGGN LGEMLGEWFS MARRRRDALI ASGAAAGLAA AFNAPLAGVL FVLEEMRNEF
NFSFINFKMV AIACVSATIV LHLIMGAHPV IPMDIFTLPS LESLWLFFIF GIVVGYVGLL
FNTVLMKTLY TLDKLPSWLK DIYVLLVGLL VGFSAYIYPG AVGGGYEIIE QSLSMYPGLG
ILSILLLVRF IFTIMCYGTG VPGGIFAPML ALGTLLGLAA SHILQGLSND ITIHPGMFAV
AGMGALFSAA VRAPVTGIIL VVEMTQNYSL ILPLMVTCLT STTVVQLAKN PPIYTQLLRR
TIKKSELEAD NQR
//
