ID A0A0W0VYC9_9GAMM Unreviewed; 331 AA.
AC A0A0W0VYC9;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Hemolysin D {ECO:0000313|EMBL:KTD25055.1};
GN ORFNames=Lisr_1280 {ECO:0000313|EMBL:KTD25055.1};
OS Legionella israelensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=454 {ECO:0000313|EMBL:KTD25055.1, ECO:0000313|Proteomes:UP000054761};
RN [1] {ECO:0000313|EMBL:KTD25055.1, ECO:0000313|Proteomes:UP000054761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bercovier 4 {ECO:0000313|EMBL:KTD25055.1,
RC ECO:0000313|Proteomes:UP000054761};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Genomic analysis of 38 Legionella species identifies large and diverse
RT effector repertoires.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTD25055.1}.
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DR EMBL; LNYH01000063; KTD25055.1; -; Genomic_DNA.
DR RefSeq; WP_058501632.1; NZ_UGOE01000001.1.
DR AlphaFoldDB; A0A0W0VYC9; -.
DR STRING; 454.Lisr_1280; -.
DR PATRIC; fig|454.4.peg.1385; -.
DR OrthoDB; 5645220at2; -.
DR Proteomes; UP000054761; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR PANTHER; PTHR30367:SF1; MULTIDRUG RESISTANCE PROTEIN MDTN; 1.
DR PANTHER; PTHR30367; P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT AAEA-RELATED; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054761};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 46..272
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT DOMAIN 273..326
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT COILED 146..173
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 331 AA; 37788 MW; 6383C1B8561CE4FE CRC64;
MNLSVFTRFK YWPQVSVLAL LLIGYSLYRY FAFYDTRSSD AYVSAHVINM APLVSGPVTG
IFIRENQAVR KGEKLIEIDP LPYLYAVRKA ESALNIARLN YENDKMALIM AQQKLKQAKL
ILALSQDHFA RYSKLEIKGD MAKITLIDLT EKIKQQEAAV EEAVQELKIA EINVDDNPIL
KAQAELDEAR YLYEHTTIKA PATGYVTNFN LRIGQYVKTG EGLFALIDTN IWWIVTRYRE
TALRLIKPGD KARIMIDMYP GKVFHGHVES IGWGINRVQS GNVAKSTLSY LEPTEDWIRI
AQRFPVRILI DDLTEKYPLR IGASATTVTY R
//
