ID A0A0W0XQY5_9GAMM Unreviewed; 545 AA.
AC A0A0W0XQY5;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN ORFNames=Lrub_1870 {ECO:0000313|EMBL:KTD46948.1};
OS Legionella rubrilucens.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=458 {ECO:0000313|EMBL:KTD46948.1, ECO:0000313|Proteomes:UP000054608};
RN [1] {ECO:0000313|EMBL:KTD46948.1, ECO:0000313|Proteomes:UP000054608}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WA-270A-C2 {ECO:0000313|EMBL:KTD46948.1,
RC ECO:0000313|Proteomes:UP000054608};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Genomic analysis of 38 Legionella species identifies large and diverse
RT effector repertoires.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTD46948.1}.
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DR EMBL; LNYT01000020; KTD46948.1; -; Genomic_DNA.
DR RefSeq; WP_058531875.1; NZ_LNYT01000020.1.
DR AlphaFoldDB; A0A0W0XQY5; -.
DR STRING; 458.Lrub_1870; -.
DR PATRIC; fig|458.5.peg.1950; -.
DR OrthoDB; 9812260at2; -.
DR Proteomes; UP000054608; Unassembled WGS sequence.
DR GO; GO:0004672; F:protein kinase activity; IEA:UniProt.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00156; REC; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.20.120.160; HPT domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR036641; HPT_dom_sf.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR008207; Sig_transdc_His_kin_Hpt_dom.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF01627; Hpt; 1.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; CheY-like; 2.
DR SUPFAM; SSF47226; Histidine-containing phosphotransfer domain, HPT domain; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50894; HPT; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 2.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW Reference proteome {ECO:0000313|Proteomes:UP000054608};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 5..112
FT /note="HPt"
FT /evidence="ECO:0000259|PROSITE:PS50894"
FT DOMAIN 128..243
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 252..368
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 408..540
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT MOD_RES 51
FT /note="Phosphohistidine"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00110"
FT MOD_RES 177
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
FT MOD_RES 301
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 545 AA; 61659 MW; 457C423AE8A338E3 CRC64;
MKEDVQHKLN ALFAMYRQSL PGKIEKLREE WTALLKDWDK ARLIDFHRNV HSLCGSAGTY
GYTELGKAAR SLEVYLKSLL ERHDPLSLNE QREIEQLLKY LELILTDCIA EAPSPGPVKV
AKKPQELLVY LLGNSDSLAQ ELKKNLEESD LKLLKITQAA SLKDMIEKKI PAAILIDLDS
LKEKETEFLT DFLSQFKRSI PLFCLAGQGD ILTRLKAIRL GSTDFYQKPL DPFLLAKKLI
QITIGQPREP YRILIIDDSI SVAEYYALIL KEAGMEARFI TNPLALIESI EDFQPDLLLM
DIYMPECTGL ELAVLLRQEP QYTGIPIVFL SSEGDRVKQL SALNLGGDDF LLKPVEPQDL
IHVLTSRAKR ARVLGSLMVK DSFTGLYNHT NIIQRLENEV SRAQRNKKPL SFAMLDIDHF
KLINDNFGHP VGDQVIRKIA ILLQNSFRRS DIIGRYGGEE FAVVLPEVQQ AHAIRICDNF
RHQVSQLQFE ANNHHFVVTL SVGIACCPPV RDVQPLINAA DKALYIAKHN GRNQVVAFNE
SLDSL
//
