ID A0A0W0YW53_LEGSP Unreviewed; 935 AA.
AC A0A0W0YW53;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Regulatory protein (GGDEF and EAL domains) {ECO:0000313|EMBL:KTD61080.1};
GN ORFNames=Lspi_2700 {ECO:0000313|EMBL:KTD61080.1};
OS Legionella spiritensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=452 {ECO:0000313|EMBL:KTD61080.1, ECO:0000313|Proteomes:UP000054877};
RN [1] {ECO:0000313|EMBL:KTD61080.1, ECO:0000313|Proteomes:UP000054877}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mt.St.Helens-9 {ECO:0000313|EMBL:KTD61080.1,
RC ECO:0000313|Proteomes:UP000054877};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Genomic analysis of 38 Legionella species identifies large and diverse
RT effector repertoires.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTD61080.1}.
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DR EMBL; LNYX01000034; KTD61080.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0W0YW53; -.
DR STRING; 452.Lspi_2700; -.
DR PATRIC; fig|452.5.peg.2989; -.
DR Proteomes; UP000054877; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00672; HAMP; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054877};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 262..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 286..338
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 532..670
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 679..933
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 935 AA; 106102 MW; 3027ACB08A1C65B3 CRC64;
MRMEKRFFQS KVARRIFLLF VLSTLIPMVI LAVFQMVNLE RQLRENGQFK VRQSIKSTGM
ALVGRLFTFT DQLNVLGHAI NHLSGTELLQ KRDQLIQLAP QFNAITVVPG KGKPQAITGE
ALSLPANVPT LLEGEGWITS DEKNARQQKD IYFVYRPDAS YLLIGRVKHN FVWQFDIKED
ALLWVLDGDG HVVYANTAIP HPRASGTKRD YSHSGAFDWT WKKRDYFVAY WDIFLKYRLK
SKEWVVVLAE PRADMASQAG NLFRIFLPAA LLALILIMYL SQFQIRRYMI PLEKLTEAAR
RVSAKRFDQP VALQSGDEFE ELGEAFNTMI KRLNRQFQAL SIMSKVDQAI LFKPDVKKVI
EIIFTGLKEL VAYDVLMIGV SQQDNPHTLQ IMTDASPDRN KAPDRVTMSQ QDLEDIGRQT
EIRISLPQEH PPVYMAWLNA IEGHFLIFPI LHHHELAALV CLGFNHKDRR DQCNTAELHD
IFNRVAVAFT HAEWEARLYY QAHYDDLTGL PNRLVLRERL NQALKQSVSG RHYGVLMFID
LDDFKDINDT MGHGVGDLLL KQVARTMEDS LLKAGTVARL GGDEFTVLLT DFKNEAEAGT
IAVEAAERLL QALSSPFTLA DNTFNVSASI GIVVFTAREG TTSDDLLKFA DMSMYQAKES
GKNCYAFFTR ELEQAVQERN ELLHDLHTAI SDNQLRLYFQ PKVDASENKL AGAEVLLRWQ
HPVKGLLSPD RFLPLAEDSD LIVAIGEWVI QAACLQIQEW QKQSLVVPPL AVNLAARHFI
HNDLVETIIR STNETGVDSR YLQFEITESS LINNFKETIT IMEQLSASGF QFALDDFGTG
YSSLSYLKKL PLHIMKIDQV FVAGLPENKQ DLSIVRAIIT LAKNLGLIIV AEGIETRIQS
ELLCEMGCSI QQGYYFSKPL PDQEFCNQFL IHSSL
//
