ID A0A0W0YYC3_LEGSP Unreviewed; 566 AA.
AC A0A0W0YYC3;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Methyltransferase {ECO:0000313|EMBL:KTD61914.1};
GN ORFNames=Lspi_2544 {ECO:0000313|EMBL:KTD61914.1};
OS Legionella spiritensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=452 {ECO:0000313|EMBL:KTD61914.1, ECO:0000313|Proteomes:UP000054877};
RN [1] {ECO:0000313|EMBL:KTD61914.1, ECO:0000313|Proteomes:UP000054877}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mt.St.Helens-9 {ECO:0000313|EMBL:KTD61914.1,
RC ECO:0000313|Proteomes:UP000054877};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Genomic analysis of 38 Legionella species identifies large and diverse
RT effector repertoires.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTD61914.1}.
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DR EMBL; LNYX01000031; KTD61914.1; -; Genomic_DNA.
DR RefSeq; WP_058484424.1; NZ_LT906457.1.
DR AlphaFoldDB; A0A0W0YYC3; -.
DR STRING; 452.Lspi_2544; -.
DR PATRIC; fig|452.5.peg.2814; -.
DR OrthoDB; 9809392at2; -.
DR Proteomes; UP000054877; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR013217; Methyltransf_12.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR006597; Sel1-like.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR44858; TETRATRICOPEPTIDE REPEAT PROTEIN 6; 1.
DR PANTHER; PTHR44858:SF1; UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE SPINDLY-RELATED; 1.
DR Pfam; PF08242; Methyltransf_12; 1.
DR Pfam; PF13414; TPR_11; 1.
DR Pfam; PF13432; TPR_16; 1.
DR Pfam; PF14559; TPR_19; 2.
DR SMART; SM00671; SEL1; 3.
DR SMART; SM00028; TPR; 9.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 7.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:KTD61914.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054877};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Transferase {ECO:0000313|EMBL:KTD61914.1}.
FT REPEAT 38..71
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 72..105
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 106..139
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 140..173
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 208..241
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 276..309
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 310..343
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 410..500
FT /note="Methyltransferase type 12"
FT /evidence="ECO:0000259|Pfam:PF08242"
SQ SEQUENCE 566 AA; 64187 MW; 9E8A067F5DBDAC87 CRC64;
MTSRPDRFAQ ACRLQQQGQL PQAIHLFEEI LQDQPGHEPA LRHLGLIHVQ LNDMTGAIDC
FKRALQAAPN DETLHNNLAN ACRKLNRFDE AIRHYQQAIA IKPDYAQAHS NLAGIYAIKN
DYKNALHHYR LAVHAQPDFT SAHYNLGLLL LKHNELQAAR TQFNNVLELN PDNIDARFYL
GVLCLEASQL HDAERAFQDV VIQDPENTQA LINLGVIALK RQQGQLAVDF FSKALALDNY
NLDARNNLAA TFMHYDRFEN ALMHYDLLLQ DAPDNTEYLY NAGVAQMALG HLNEAIGHFE
TLLALEPEHF AALNNLAAVY LRLEDRQQAK TLLRRAVAAN PEDPASRHML QALEGTTTSG
QTCEKYAANL FNNYALYYDQ HMQGPLHYSL PRHIQQIGEA LSLNDVERTL DLGCGTGLTG
EVLRSFSRDL TGVDISSKML AQAKEKRLYD RTVESELLTF LNKDPHHYGL IVAADVLPYF
GELDSLFAAI SRRLVPEGYF LFSTEISSSQ SWQLQESARF SHHPDYLRRL CQKHHLDILE
QKQVIARHQN ERGLSELLFT TRLKSV
//
