ID A0A0W0YZL4_LEGSP Unreviewed; 450 AA.
AC A0A0W0YZL4;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Adenylate cyclase {ECO:0000313|EMBL:KTD61958.1};
GN ORFNames=Lspi_2588 {ECO:0000313|EMBL:KTD61958.1};
OS Legionella spiritensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=452 {ECO:0000313|EMBL:KTD61958.1, ECO:0000313|Proteomes:UP000054877};
RN [1] {ECO:0000313|EMBL:KTD61958.1, ECO:0000313|Proteomes:UP000054877}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mt.St.Helens-9 {ECO:0000313|EMBL:KTD61958.1,
RC ECO:0000313|Proteomes:UP000054877};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Genomic analysis of 38 Legionella species identifies large and diverse
RT effector repertoires.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTD61958.1}.
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DR EMBL; LNYX01000031; KTD61958.1; -; Genomic_DNA.
DR RefSeq; WP_058484467.1; NZ_LT906457.1.
DR AlphaFoldDB; A0A0W0YZL4; -.
DR STRING; 452.Lspi_2588; -.
DR PATRIC; fig|452.5.peg.2859; -.
DR OrthoDB; 9806704at2; -.
DR Proteomes; UP000054877; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054877};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 38..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 152..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 265..397
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 450 AA; 49751 MW; 7BD7C2FE73279E06 CRC64;
MASSHALRKL IFGTSPKISF PSHVQAAINR QQNDSEKLIS WVLLAIVVIF SVLYIVSPKT
FSPTVKFAPV PWALSAYFIF SLIRLYAAYR GYLVNWFLLL SIIVDIMLLM TLIWSFHVQY
EQPPSFYLKA PTLQYLFIFI ALRTLRFQAK YVLTIGMVAA VGWFALILFA VFFSPHGTVT
RDYVLYLTSN HILIGGEIDK IISILMVTAI LTIAVLRGQH LLSQAVAETM ATTELSKFFV
PEIASTIIES GANLKPGYGE SRDVTILHCD IRGFTKTSKL CSPAEVMSML TEYQARVVKI
IRKHQGSVDK FLGDGILTSF NALPKTPAHA AKALSAAGDI LTTIQEWNEQ RDKEGKQPVK
IGISITTGSV VLGIVGDATR MEYTVIGDPV NLAAKLDKHC RVEKCSILAT KETLDLAIAQ
GYVQPPTIEI LLQRTVEGVA EPVDLAILAR
//
