ID A0A0W0Z4K4_LEGSP Unreviewed; 441 AA.
AC A0A0W0Z4K4;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Membrane fusion protein (MFP) family protein {ECO:0000256|RuleBase:RU365093};
GN Name=lssD_1 {ECO:0000313|EMBL:KTD64080.1};
GN ORFNames=Lspi_1599 {ECO:0000313|EMBL:KTD64080.1};
OS Legionella spiritensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=452 {ECO:0000313|EMBL:KTD64080.1, ECO:0000313|Proteomes:UP000054877};
RN [1] {ECO:0000313|EMBL:KTD64080.1, ECO:0000313|Proteomes:UP000054877}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mt.St.Helens-9 {ECO:0000313|EMBL:KTD64080.1,
RC ECO:0000313|Proteomes:UP000054877};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Genomic analysis of 38 Legionella species identifies large and diverse
RT effector repertoires.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|RuleBase:RU365093}; Single-pass membrane protein
CC {ECO:0000256|RuleBase:RU365093}.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477, ECO:0000256|RuleBase:RU365093}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTD64080.1}.
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DR EMBL; LNYX01000014; KTD64080.1; -; Genomic_DNA.
DR RefSeq; WP_058483509.1; NZ_LT906457.1.
DR AlphaFoldDB; A0A0W0Z4K4; -.
DR STRING; 452.Lspi_1599; -.
DR PATRIC; fig|452.5.peg.1758; -.
DR Proteomes; UP000054877; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR InterPro; IPR010129; T1SS_HlyD.
DR NCBIfam; TIGR01843; type_I_hlyD; 1.
DR PANTHER; PTHR30386:SF17; ALKALINE PROTEASE SECRETION PROTEIN APRE; 1.
DR PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR Pfam; PF13437; HlyD_3; 1.
DR PRINTS; PR01490; RTXTOXIND.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|RuleBase:RU365093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU365093}; Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|RuleBase:RU365093};
KW Reference proteome {ECO:0000313|Proteomes:UP000054877};
KW Transmembrane {ECO:0000256|RuleBase:RU365093};
KW Transmembrane helix {ECO:0000256|RuleBase:RU365093};
KW Transport {ECO:0000256|RuleBase:RU365093}.
FT TRANSMEM 17..39
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365093"
FT COILED 165..199
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 253..294
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 441 AA; 49766 MW; 242E5928501A27EB CRC64;
MDNGNPHKLP ETSESPIITS ILIFGFIILI VFVGGFLLWS MLFRLDAAAV APGKLMVQNV
RKTVQHMEGG IIKKIYIDEG SAVKANTPLI KLDDTQAKAS VDLLQGQVYE NLASESRIFA
ELNNEKTIDY PEELLQKATN PKVKKIISGQ NKLFTANTRS YEGQIKVLNE RIEEFHHEIK
SLEAQVDSGT EQLSLINEEI KAVEYLEARK LIDKPRLLAL RREAARLTGN RGEHLGLVAK
AHQAISETKS QIYTLMESRR RDLLQNLREI QQKLADLQEK LKAAQDVLQR TLIAAPLTGT
VIGLKKHTVG GVITPGQDIL DIIPSEDQLI VEAEVDPLDI DIVRPGLTAK VRLSAYKQRT
TPFIEGKVKL VSADVFEDQV TKKQYYKVHI LLDKKDLQQL KHIHLYPGMP VQVMIIVEKR
TAFDYFITPI QDSFERAFHE Q
//
