ID A0A0W0Z5E8_LEGSP Unreviewed; 324 AA.
AC A0A0W0Z5E8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Guanylate cyclase domain-containing protein {ECO:0000259|PROSITE:PS50125};
GN ORFNames=Lspi_1582 {ECO:0000313|EMBL:KTD64063.1};
OS Legionella spiritensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=452 {ECO:0000313|EMBL:KTD64063.1, ECO:0000313|Proteomes:UP000054877};
RN [1] {ECO:0000313|EMBL:KTD64063.1, ECO:0000313|Proteomes:UP000054877}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mt.St.Helens-9 {ECO:0000313|EMBL:KTD64063.1,
RC ECO:0000313|Proteomes:UP000054877};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Genomic analysis of 38 Legionella species identifies large and diverse
RT effector repertoires.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTD64063.1}.
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DR EMBL; LNYX01000014; KTD64063.1; -; Genomic_DNA.
DR RefSeq; WP_058483496.1; NZ_LT906457.1.
DR AlphaFoldDB; A0A0W0Z5E8; -.
DR STRING; 452.Lspi_1582; -.
DR PATRIC; fig|452.5.peg.1740; -.
DR OrthoDB; 8196020at2; -.
DR Proteomes; UP000054877; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054877};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 160..280
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 324 AA; 37089 MW; D4446B9330BAD22B CRC64;
MRALFSLILI VLRLSHFLLW VLILLCLFGM IKPYIKNISS YTYLQPIVKV ENTINIAVKK
TIPTTIADKD ASRIITIAVL LFISIYISHL IAGPLQKFKA RIKLREYRKK AVTAPQKILI
SQIEEQLDSS VNFKAKNRQE LLKDFVRLKK ELEKSGRTLS FLSIDVVDST GMKQDEDPVI
VENDFNQYHD YINQKFKEHG YIKAAWTPDG VMACFNTTEQ AISAAKDIIL GLVHFNKSVK
MMQNDFHVRC GINTGFVYYD LSTPLEEFSD RVIDIAGHMQ KHAPVDSVLV AKEIIKPIKS
SDVFRKSDSM VDGLEVFEWR SSRK
//
