ID   A0A0W0Z5S0_LEGSP        Unreviewed;       538 AA.
AC   A0A0W0Z5S0;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Alkaline phosphatase {ECO:0000313|EMBL:KTD64505.1};
GN   ORFNames=Lspi_1312 {ECO:0000313|EMBL:KTD64505.1};
OS   Legionella spiritensis.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC   Legionellaceae; Legionella.
OX   NCBI_TaxID=452 {ECO:0000313|EMBL:KTD64505.1, ECO:0000313|Proteomes:UP000054877};
RN   [1] {ECO:0000313|EMBL:KTD64505.1, ECO:0000313|Proteomes:UP000054877}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Mt.St.Helens-9 {ECO:0000313|EMBL:KTD64505.1,
RC   ECO:0000313|Proteomes:UP000054877};
RA   Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA   Pupko T., Shuman H.A., Segal G.;
RT   "Genomic analysis of 38 Legionella species identifies large and diverse
RT   effector repertoires.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KTD64505.1}.
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DR   EMBL; LNYX01000013; KTD64505.1; -; Genomic_DNA.
DR   RefSeq; WP_058483228.1; NZ_LT906457.1.
DR   AlphaFoldDB; A0A0W0Z5S0; -.
DR   STRING; 452.Lspi_1312; -.
DR   PATRIC; fig|452.5.peg.1450; -.
DR   OrthoDB; 9766127at2; -.
DR   Proteomes; UP000054877; Unassembled WGS sequence.
DR   GO; GO:0004035; F:alkaline phosphatase activity; IEA:InterPro.
DR   CDD; cd16016; AP-SPAP; 1.
DR   Gene3D; 3.30.1360.150; -; 1.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR026263; Alkaline_phosphatase_prok.
DR   InterPro; IPR002591; Phosphodiest/P_Trfase.
DR   PANTHER; PTHR10151:SF120; BIS(5'-ADENOSYL)-TRIPHOSPHATASE; 1.
DR   PANTHER; PTHR10151; ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE; 1.
DR   Pfam; PF01663; Phosphodiest; 1.
DR   PIRSF; PIRSF031924; Pi-irrepressible_AP; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE   4: Predicted;
KW   Phosphoprotein {ECO:0000256|PIRSR:PIRSR031924-50};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054877};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..538
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5006918303"
FT   ACT_SITE        73
FT                   /note="Phosphothreonine intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR031924-50"
FT   BINDING         94
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR031924-51"
FT   BINDING         156..158
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR031924-51"
SQ   SEQUENCE   538 AA;  60256 MW;  AEF30FCC4CA937B0 CRC64;
     MKKLLCTILY LTTIPLHAAN PPPRLIVQLV VDQLRGDLLY QYQDKFGANG FNYLLNHSIN
     YQNAHHPHAH TVTCVGHATI ATGSYPMLHG VVANDWFDPM QGKSTYCMAD RNSKILPIHP
     SDKDSEGRSP AHLLASTLSD ELILAKRGRA FGVSFKDRAA ITMAGHAGKA FWFDKHNGGF
     ITSNYYYQHY PQWVQKWNQG YQPANRTWAL KNPARDYNYA DAPRFEHRFP GFGQKFPHHL
     GEPSTPKYLK YLSMTPFADE LTTDFAIELL RAEQLGAVPG KTDYLSISFS ATDAIGHQFG
     PNSLESEDNL LRLDETIARL LAVIDQQVGL ANTLVILTAD HGVSDSTVYL AAHHLYENHS
     LKEQKLRHVL DAALGQHFQL PADAVRHIEL PYVYLNHQII KEHQLSVGTV TTYLVEILRQ
     LPGVFQAYPM PLAATEHDWL SAKVDKMAFP GRSGDLYIVA PPYQALADKS EQRTSHGTPW
     NYDSYVPLLF VHPGIKPRRI AKPAYTTDIA STLATILKIK APSANVGQPL PEVTNHFE
//