ID   A0A0W1A5I4_9GAMM        Unreviewed;       357 AA.
AC   A0A0W1A5I4;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Multidrug resistance protein {ECO:0000313|EMBL:KTD76504.1};
GN   ORFNames=Lwal_2226 {ECO:0000313|EMBL:KTD76504.1};
OS   Legionella waltersii.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC   Legionellaceae; Legionella.
OX   NCBI_TaxID=66969 {ECO:0000313|EMBL:KTD76504.1, ECO:0000313|Proteomes:UP000054729};
RN   [1] {ECO:0000313|EMBL:KTD76504.1, ECO:0000313|Proteomes:UP000054729}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51914 {ECO:0000313|EMBL:KTD76504.1,
RC   ECO:0000313|Proteomes:UP000054729};
RA   Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA   Pupko T., Shuman H.A., Segal G.;
RT   "Genomic analysis of 38 Legionella species identifies large and diverse
RT   effector repertoires.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KTD76504.1}.
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DR   EMBL; LNZB01000051; KTD76504.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0W1A5I4; -.
DR   STRING; 66969.Lwal_2226; -.
DR   PATRIC; fig|66969.6.peg.2421; -.
DR   OrthoDB; 9811754at2; -.
DR   Proteomes; UP000054729; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.30.170; -; 1.
DR   Gene3D; 2.40.50.100; -; 1.
DR   InterPro; IPR032317; HlyD_D23.
DR   PANTHER; PTHR30367:SF1; MULTIDRUG RESISTANCE PROTEIN MDTN; 1.
DR   PANTHER; PTHR30367; P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT AAEA-RELATED; 1.
DR   Pfam; PF16576; HlyD_D23; 1.
DR   SUPFAM; SSF111369; HlyD-like secretion proteins; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054729};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        35..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          69..294
FT                   /note="RND efflux pump membrane fusion protein barrel-
FT                   sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF16576"
FT   COILED          131..210
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   357 AA;  40780 MW;  DE8269F015BBCEAD CRC64;
     MNEDYKKTLH LLGNTLNAFF TKTLPHFFKQ WKGHLNLPII VVSLALLIGL FHFFSYLIPF
     TDNAFVVTNI TPVAADVSGF ITKIYVKNGQ QVKKDSPIFE VYKAPYQLAY DQAKAEYQEG
     LKKIIVFEKQ IDRTRALIKA TEAELEKAEY ALRLKRNKSV AEAVSVLEIK NLSYDVAALS
     NRKASLLREV EVLQAQIDQQ QHTVASLKAK QDNAKVNLDL TIVRAPGDGV IDNMYVSPNT
     PIERHKPVFS FIDTSNYYIQ ANFNETDLRY VRPGDKAYII LRMYYFDKVF HGIVVNSLWA
     AERQVTAPKS QIQVVSNQNE WLLLPQRFPI QIKILDPDPK YPLNPGSSAY VYISTKK
//