ID A0A0W1CI55_9SPHN Unreviewed; 381 AA.
AC A0A0W1CI55;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=beta-lactamase {ECO:0000256|ARBA:ARBA00012865};
DE EC=3.5.2.6 {ECO:0000256|ARBA:ARBA00012865};
GN ORFNames=ATE71_18165 {ECO:0000313|EMBL:KTE05502.1};
OS Sphingopyxis sp. H115.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingopyxis.
OX NCBI_TaxID=1759073 {ECO:0000313|EMBL:KTE05502.1, ECO:0000313|Proteomes:UP000054021};
RN [1] {ECO:0000313|EMBL:KTE05502.1, ECO:0000313|Proteomes:UP000054021}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H115 {ECO:0000313|EMBL:KTE05502.1,
RC ECO:0000313|Proteomes:UP000054021};
RA Zhang Y., Guo Z.;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a beta-lactam + H2O = a substituted beta-amino acid;
CC Xref=Rhea:RHEA:20401, ChEBI:CHEBI:15377, ChEBI:CHEBI:35627,
CC ChEBI:CHEBI:140347; EC=3.5.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00001526};
CC -!- SIMILARITY: Belongs to the class-A beta-lactamase family.
CC {ECO:0000256|ARBA:ARBA00009009}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTE05502.1}.
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DR EMBL; LNSA01000032; KTE05502.1; -; Genomic_DNA.
DR RefSeq; WP_058804754.1; NZ_LNSA01000032.1.
DR AlphaFoldDB; A0A0W1CI55; -.
DR STRING; 1759073.ATE71_18165; -.
DR OrthoDB; 9784149at2; -.
DR Proteomes; UP000054021; Unassembled WGS sequence.
DR GO; GO:0008800; F:beta-lactamase activity; IEA:UniProtKB-EC.
DR GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR045155; Beta-lactam_cat.
DR InterPro; IPR000871; Beta-lactam_class-A.
DR PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR PANTHER; PTHR35333:SF3; BETA-LACTAMASE2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13354; Beta-lactamase2; 1.
DR PRINTS; PR00118; BLACTAMASEA.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW Hydrolase {ECO:0000313|EMBL:KTE05502.1}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..381
FT /note="beta-lactamase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006920998"
FT DOMAIN 94..353
FT /note="Beta-lactamase class A catalytic"
FT /evidence="ECO:0000259|Pfam:PF13354"
SQ SEQUENCE 381 AA; 40278 MW; E1229445F8E46C5F CRC64;
MKFEYSGRAL LAVTMSAAVL AGCVSSAAIV PQPRAQQPAA ARGPAGSVTV PIGQPVRSAM
PAPRGTIDPG FRRAPDGLND RLYSLWRAFP GKTGIAVQRI DGEWTLSQRG DELFPQQSVS
KLWVALAVLD AVDQGRLRMD QPVRIGPEDL TLFHQPIAAR VRSEGSVTMT VRELIETAIT
HSDNTANDSL LRTVGGPGAV RAFISKMDLG AIRFGPGERL LQSGTAGLTW QQSYSIGRNF
QAARSTLAPA TRRAAMDNYL ANPVDGASPA AIASALTRLA RGTLLSPEST DYLLGVMSRT
RSGPKRLKAG LPAGWKFVHK TGTGQDLNGM TAGYNDIGIA TAPDGTRYAI VVMLGTTTSS
IPSRMALMQA VSGAVAEFHG K
//
