ID A0A0W1F4Y0_9SPHN Unreviewed; 528 AA.
AC A0A0W1F4Y0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Glucose-methanol-choline oxidoreductase {ECO:0000313|EMBL:KTE37527.1};
GN ORFNames=ATE62_13505 {ECO:0000313|EMBL:KTE37527.1};
OS Sphingopyxis sp. HIX.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingopyxis.
OX NCBI_TaxID=1759074 {ECO:0000313|EMBL:KTE37527.1, ECO:0000313|Proteomes:UP000053691};
RN [1] {ECO:0000313|Proteomes:UP000053691}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HIX {ECO:0000313|Proteomes:UP000053691};
RA Gomez-Alvarez V., Revetta R.P.;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790, ECO:0000256|RuleBase:RU003968}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTE37527.1}.
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DR EMBL; LNSB01000026; KTE37527.1; -; Genomic_DNA.
DR RefSeq; WP_058809214.1; NZ_LNSB01000026.1.
DR AlphaFoldDB; A0A0W1F4Y0; -.
DR STRING; 1759074.ATE62_13505; -.
DR Proteomes; UP000053691; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00623; GMC_OXRED_1; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU003968}.
FT DOMAIN 79..102
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00623"
FT DOMAIN 251..265
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
FT BINDING 89..92
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 216
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 528 AA; 56572 MW; C7B7B995A1F3DF12 CRC64;
MDAFDIIVIG GGSAGSAAAG RLAEDGRRTV CLVEAGGTND IVRVKTPGFM PFIPKASNYR
YDTLPQKGLN GRIGYQPRGR GLGGSSAINA MVYIRGHAFD YDQWEALGAT GWSYADVLPY
FKRSEGNERG ADYFHGSDGP LNVMDQRWPN VTSRRFVESA AALQLPRTAD FNGANQEGFG
FYQVTQKAGE RWSAARAYVE PLRAHGNFTV RTKALVEKIL VEDGRATGVV IRRGGSRETL
RARGGVILSA GAFGSPQILM LSGIGPAAHL KEQGVAVVAD RAGVGADLQD HIDYVSSWET
RSTDPFGDSL GGTWRMVKAI FEHRTQRTGI MTTCFAEAGG FWKSHPDLPA PDIQYHFVPA
MLEDHGRAKV KGHGFSCHAC VLRPESRGSV RLASSDAGAA PAIDPGFLTD ERDMATLRAG
VRMMHRIAAA PPLSDYAGVD RHPVDLADDA ALDALIRSRA DTVYHPVGTC RMGSDDAAVV
DPTLKARGID GLWVADASIM PRLVSGNTNA PSIMIGERAA DFVKAALA
//
