ID A0A0W1F6S8_9SPHN Unreviewed; 498 AA.
AC A0A0W1F6S8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=4-hydroxybutyryl-CoA dehydratase {ECO:0000313|EMBL:KTE38351.1};
GN ORFNames=ATE62_11020 {ECO:0000313|EMBL:KTE38351.1};
OS Sphingopyxis sp. HIX.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingopyxis.
OX NCBI_TaxID=1759074 {ECO:0000313|EMBL:KTE38351.1, ECO:0000313|Proteomes:UP000053691};
RN [1] {ECO:0000313|Proteomes:UP000053691}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HIX {ECO:0000313|Proteomes:UP000053691};
RA Gomez-Alvarez V., Revetta R.P.;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTE38351.1}.
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DR EMBL; LNSB01000020; KTE38351.1; -; Genomic_DNA.
DR RefSeq; WP_058806758.1; NZ_LNSB01000020.1.
DR AlphaFoldDB; A0A0W1F6S8; -.
DR STRING; 1759074.ATE62_11020; -.
DR Proteomes; UP000053691; Unassembled WGS sequence.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR Gene3D; 1.10.3140.10; 4-hydroxybutyryl-coa dehydratase, domain 1; 1.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 1.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR InterPro; IPR004925; HpaB/PvcC/4-BUDH.
DR InterPro; IPR024719; HpaB/PvcC/4-BUDH_C.
DR InterPro; IPR024674; HpaB/PvcC/4-BUDH_N.
DR PANTHER; PTHR36117; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR PANTHER; PTHR36117:SF3; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR Pfam; PF03241; HpaB; 1.
DR Pfam; PF11794; HpaB_N; 1.
DR PIRSF; PIRSF000331; HpaA_HpaB; 1.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|PIRSR:PIRSR000331-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 22..289
FT /note="HpaB/PvcC/4-BUDH N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11794"
FT DOMAIN 296..494
FT /note="HpaB/PvcC/4-BUDH C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03241"
FT BINDING 206
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000331-2"
SQ SEQUENCE 498 AA; 55100 MW; 4E34F9D3262ECB5B CRC64;
MPIHPREESA ADRWSRFRPI VTGDDYVASL RGRGVEVWLF GERVEEPVDH PIIRPSINAL
KMTYDLALAE PELATAHSDL IDAPVNRFLH IVGSPQDLVM KNRMQRKMGQ LTGTCFQRCA
GLDTISVLHS ITFDIDAKHG TPYHQRYLDF MAHAQRANII IGAGMTDPKG DRSKRPHEQA
DPDMFLHVTK RTDAGVYVTG AKAHMTGGLN SHWICVMPTM NMGEADRDFA IVGLVPGDAT
GITYIYGRQS CDTRAMEAGD IDQGNARFGG QETLVVFDNV FIPHEHVLMD GEYEFAQDMV
ARFTAYHRAS YVCKTGLGDV MVGAAAQVAD YNGAEAASHI KDKLVEMTHL NETIYSSAIA
SSHEAKPLPS GIYMNDAMLA NVCKHNVTRF PYEISRLAQD LAGGIMVTMP SDADFKNEAI
GPILEKYMKG KHNVPVEYRQ RILRLIENMT LGRNAVGYLT ESMHGAGSPQ AQRIQILRGM
EVEKKKGLAR DLAGIAEE
//
