ID A0A0W1LAP8_9GAMM Unreviewed; 627 AA.
AC A0A0W1LAP8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Propionate--CoA ligase {ECO:0000313|EMBL:KTF17001.1};
GN Name=prpE {ECO:0000313|EMBL:KTF17001.1};
GN ORFNames=ATS75_06050 {ECO:0000313|EMBL:KTF17001.1};
OS Pseudoalteromonas sp. H105.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Pseudoalteromonadaceae; Pseudoalteromonas.
OX NCBI_TaxID=1348393 {ECO:0000313|EMBL:KTF17001.1, ECO:0000313|Proteomes:UP000054685};
RN [1] {ECO:0000313|EMBL:KTF17001.1, ECO:0000313|Proteomes:UP000054685}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H105 {ECO:0000313|EMBL:KTF17001.1,
RC ECO:0000313|Proteomes:UP000054685};
RA Duhaime M.B., Sullivan M.B., Wichels A.;
RT "Six Pseudoalteromonas strains isolated from surface waters of Kabeltonne
RT offshore Helgoland, North Sea.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTF17001.1}.
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DR EMBL; LOFH01000002; KTF17001.1; -; Genomic_DNA.
DR RefSeq; WP_058559527.1; NZ_LOFH01000002.1.
DR AlphaFoldDB; A0A0W1LAP8; -.
DR STRING; 1348393.ATS75_06050; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000054685; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR CDD; cd05967; PrpE; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43347; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43347:SF3; ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:KTF17001.1}.
FT DOMAIN 5..58
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 66..446
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 511..590
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 627 AA; 69167 MW; 7EDF9813271CB3FC CRC64;
MSGQYQQQYE HFKNDPAQFW LAQSKRIPWF TPPSTAYTQD DNNFYHWFAD GQLNTCYLAL
DHHVDAGFGE QTALIYDSPV TNTKKQYTYA ELQHEVAKFA GVMRDLGVEQ GDCVVIYMPM
IPEAVIGMLA CARIGAVHSV VFGGFAAHEL AVRIDDAKPK LVLSASCGVE VNTVIEYKPL
IDNALALASH KIAHCVIYQR EYVTAHLMPG RDINWAEAMQ TAQPVAPVAL QGDHPLYILY
TSGTTGTPKG VVRENAGHAV AMHYSMETVY GMKPGDVFWA ASDIGWVVGH SYIVYAPLIY
RCTTVLYEGK PVRTPDASAF WRVVAEHKVN ALFSAPTAFR AIKKEDPKAL GFKQYDTSSL
KRLFLAGERL DPPTYNWLKA HTNLPVLDHW WQTETGWAIA CNPIGIETLE TKPGSATVPT
PGFDVQILNM EGEQCAPNES GAVVIKLPLP PGCLPTIWQN DERFKAGYLN EYPGYYLSGD
GGYIDDDGYL FIMGRTDDVI NVAGHRLSTG EMEEIVASHD AVAECAVFGV NDSLKGQLPM
AMIVLKDDCT DEASLVEQQL VTLVREQIGA IACLKTIVHV ARLPKTRSGK ILRKNLRQLV
DGEELNVPST VDDASIFDEI KSSLVAS
//
