ID A0A0W1LE77_9GAMM Unreviewed; 293 AA.
AC A0A0W1LE77;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Oxidoreductase {ECO:0000313|EMBL:KTF18016.1};
GN ORFNames=ATS75_00950 {ECO:0000313|EMBL:KTF18016.1};
OS Pseudoalteromonas sp. H105.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Pseudoalteromonadaceae; Pseudoalteromonas.
OX NCBI_TaxID=1348393 {ECO:0000313|EMBL:KTF18016.1, ECO:0000313|Proteomes:UP000054685};
RN [1] {ECO:0000313|EMBL:KTF18016.1, ECO:0000313|Proteomes:UP000054685}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H105 {ECO:0000313|EMBL:KTF18016.1,
RC ECO:0000313|Proteomes:UP000054685};
RA Duhaime M.B., Sullivan M.B., Wichels A.;
RT "Six Pseudoalteromonas strains isolated from surface waters of Kabeltonne
RT offshore Helgoland, North Sea.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the HIBADH-related family.
CC {ECO:0000256|ARBA:ARBA00009080}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTF18016.1}.
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DR EMBL; LOFH01000001; KTF18016.1; -; Genomic_DNA.
DR RefSeq; WP_058558557.1; NZ_LOFH01000001.1.
DR AlphaFoldDB; A0A0W1LE77; -.
DR STRING; 1348393.ATS75_00950; -.
DR OrthoDB; 9786703at2; -.
DR Proteomes; UP000054685; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002204; 3-OH-isobutyrate_DH-rel_CS.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43060; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR PANTHER; PTHR43060:SF15; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00895; 3_HYDROXYISOBUT_DH; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 5..158
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 167..284
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
FT ACT_SITE 173
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 293 AA; 30632 MW; C4CFB4DEDA7F2111 CRC64;
MSMNVSFIGL GVMGYPMAGH LANAGHTVSV YNRTTAKAQQ WAGQFKGEVA LTPALAAQGA
DIVFMCVGND DDLRSVVYGE DGVLAGMAEG TILVDHTTTS AEVAREVSAK AALQHVAFID
APVSGGQAGA ENGVLTVMAG GDEAVFAKVQ PVMAAFSRFS QLLGEVGAGQ LCKMVNQICI
AGVVQGLAEG LHFAKQAGLD GEKVIETIAK GAAGSWQMEN RHKTMLAGEY EFGFAVDWMR
KDLGIALDEA KNNGATLPMT ATVDQYYADV QALGGGRYDT SSLLARIEAL HKK
//
