ID A0A0W1R3D4_9EURY Unreviewed; 684 AA.
AC A0A0W1R3D4;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=beta-galactosidase {ECO:0000256|ARBA:ARBA00012756};
DE EC=3.2.1.23 {ECO:0000256|ARBA:ARBA00012756};
GN ORFNames=AUR64_02710 {ECO:0000313|EMBL:KTG07766.1};
OS Haloprofundus marisrubri.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Haloprofundus.
OX NCBI_TaxID=1514971 {ECO:0000313|EMBL:KTG07766.1, ECO:0000313|Proteomes:UP000054387};
RN [1] {ECO:0000313|EMBL:KTG07766.1, ECO:0000313|Proteomes:UP000054387}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB9 {ECO:0000313|EMBL:KTG07766.1,
RC ECO:0000313|Proteomes:UP000054387};
RA Zhang G., Stingl U., Rashid M.;
RT "Haloprofundus marisrubri gen. nov., sp. nov., an extremely halophilic
RT archaeon isolated from the Discovery deep brine-seawater interface in the
RT Red Sea.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC in beta-D-galactosides.; EC=3.2.1.23;
CC Evidence={ECO:0000256|ARBA:ARBA00001412};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 42 family.
CC {ECO:0000256|ARBA:ARBA00005940}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTG07766.1}.
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DR EMBL; LOPU01000040; KTG07766.1; -; Genomic_DNA.
DR RefSeq; WP_058583597.1; NZ_LOPU01000040.1.
DR AlphaFoldDB; A0A0W1R3D4; -.
DR STRING; 1514971.AUR64_02710; -.
DR OrthoDB; 85141at2157; -.
DR Proteomes; UP000054387; Unassembled WGS sequence.
DR GO; GO:0009341; C:beta-galactosidase complex; IEA:InterPro.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd03143; A4_beta-galactosidase_middle_domain; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR013738; Beta_galactosidase_Trimer.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR003476; Glyco_hydro_42.
DR InterPro; IPR013529; Glyco_hydro_42_N.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR36447; BETA-GALACTOSIDASE GANA; 1.
DR PANTHER; PTHR36447:SF2; BETA-GALACTOSIDASE YESZ; 1.
DR Pfam; PF02449; Glyco_hydro_42; 1.
DR Pfam; PF08532; Glyco_hydro_42M; 1.
DR PIRSF; PIRSF001084; B-galactosidase; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE 3: Inferred from homology;
FT DOMAIN 6..388
FT /note="Glycoside hydrolase family 42 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02449"
FT DOMAIN 409..614
FT /note="Beta-galactosidase trimerisation"
FT /evidence="ECO:0000259|Pfam:PF08532"
SQ SEQUENCE 684 AA; 76691 MW; E49670C19ED3A9DF CRC64;
MNIGVCYFPE HWPEERLQRD IEQMAEAGLR YVRMGEFSWS RLEPEPGSYD FEWLREAVSL
IGDHGMQAVL CTPTATPPKW LVDEYPSIRQ KEVDGTPRHY GSRRHYCYNS EIYRRETRRI
TEALAEAFAD DPAVAGWQTD NEYGCHGTIR CYCDDCATAF RTWLKEKYGD VETLNESWGT
AFWSQNLNSF AQVDPPRHTA AEHHPARLLD YYRFSSDSVV EYNRLQTQLL REANDDWFVT
HNFMGHFGAL DAYDVSEDLD FASWDSYPTG HVQERSTPAT KEQLRAGDPD QIAFNHDLYR
SATGSPFWVM EQQPGDINWP PYSAQPGDEA MRLWAQFAAA HGAGVVSYFR WRQCLMGQEQ
YHSGLLAPNG TPDRGYHDAT RAAAEFDELV GERETDTGVD GATTAVPEAN VAVLHDYDNL
WALEIEPNTP DFDYWEHVET YYAALQARSV TVDVVPPSAE LSGYDAVVAP TLYLADEDLA
ETLESYVSSG GELLVTMRSG VKDPYNKLHE TQQPGPLTDL LGAEVAQFES VPERIESGVS
YGGERYDGHI WNDWLSPVAD SAEVVGRYDG ELADGDAAIV HNSVGDGSVL YVGTWPERAL
ADELVGDLLT RADVETTPRL PDQVRLARRD GLTWVTNFSS DPVSVSVDAD ADARWLVGDE
SVDSYDVAVT DAAPATLSVE QERE
//
