ID   A0A0W4ZBT3_PNEJ7        Unreviewed;      1104 AA.
AC   A0A0W4ZBT3;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   08-NOV-2023, entry version 29.
DE   RecName: Full=Spc7 kinetochore protein domain-containing protein {ECO:0000259|SMART:SM00787};
GN   ORFNames=T551_03653 {ECO:0000313|EMBL:KTW25817.1};
OS   Pneumocystis jirovecii (strain RU7) (Human pneumocystis pneumonia agent).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Pneumocystomycetes; Pneumocystaceae; Pneumocystis.
OX   NCBI_TaxID=1408657 {ECO:0000313|EMBL:KTW25817.1, ECO:0000313|Proteomes:UP000053447};
RN   [1] {ECO:0000313|Proteomes:UP000053447}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RU7 {ECO:0000313|Proteomes:UP000053447};
RX   PubMed=26899007; DOI=10.1038/ncomms10740;
RA   Ma L., Chen Z., Huang D.W., Kutty G., Ishihara M., Wang H., Abouelleil A.,
RA   Bishop L., Davey E., Deng R., Deng X., Fan L., Fantoni G., Fitzgerald M.,
RA   Gogineni E., Goldberg J.M., Handley G., Hu X., Huber C., Jiao X., Jones K.,
RA   Levin J.Z., Liu Y., Macdonald P., Melnikov A., Raley C., Sassi M.,
RA   Sherman B.T., Song X., Sykes S., Tran B., Walsh L., Xia Y., Yang J.,
RA   Young S., Zeng Q., Zheng X., Stephens R., Nusbaum C., Birren B.W.,
RA   Azadi P., Lempicki R.A., Cuomo C.A., Kovacs J.A.;
RT   "Genome analysis of three Pneumocystis species reveals adaptation
RT   mechanisms to life exclusively in mammalian hosts.";
RL   Nat. Commun. 7:10740-10740(2016).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KTW25817.1}.
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DR   EMBL; LFWA01000020; KTW25817.1; -; Genomic_DNA.
DR   RefSeq; XP_018227864.1; XM_018375916.1.
DR   AlphaFoldDB; A0A0W4ZBT3; -.
DR   STRING; 1408657.A0A0W4ZBT3; -.
DR   GeneID; 28942171; -.
DR   VEuPathDB; FungiDB:T551_03653; -.
DR   eggNOG; ENOG502S20P; Eukaryota.
DR   OrthoDB; 1706190at2759; -.
DR   Proteomes; UP000053447; Unassembled WGS sequence.
DR   InterPro; IPR040850; Knl1_RWD_C.
DR   InterPro; IPR033338; Spc105/Spc7.
DR   InterPro; IPR013253; Spc7_domain.
DR   PANTHER; PTHR28260; SPINDLE POLE BODY COMPONENT SPC105; 1.
DR   PANTHER; PTHR28260:SF1; SPINDLE POLE BODY COMPONENT SPC105; 1.
DR   Pfam; PF18210; Knl1_RWD_C; 1.
DR   Pfam; PF15402; MELT_2; 2.
DR   Pfam; PF08317; Spc7; 1.
DR   SMART; SM00787; Spc7; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053447}.
FT   DOMAIN          640..951
FT                   /note="Spc7 kinetochore protein"
FT                   /evidence="ECO:0000259|SMART:SM00787"
FT   REGION          54..73
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          823..910
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        57..73
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1104 AA;  126453 MW;  BAF2E57431D6E6E3 CRC64;
     MDNHTVIGIM QVALKEEAEN DSGNDEIKKS RKLKGLNRRV SFASHASVRL FEKEQEFRSP
     NSTPSSQSSL LSDQKSLLSP IKRNFKYQKS LLLNNSPKTP SPIKCISPVK SSRLYINSPV
     PISQGHKVLD DLNQHDSEMV EDACCFNFQE SVSKDHFFDY KNNSNSKDID GEMTMDLTEI
     ISKSVFEEKK SDEITVNMIN TATGSVFEED LAEKTMDLTK VIPGSIFQGN KENFTAHSTE
     IVDNASFEKN SLEEVKMDLT LALGKIHASK NAIDHINFHL QSDKNSNSNE NQDIFVKENN
     QLSESLGIRF MELENSVDSK FLNNDIDSDK DIAEIAGTIL KRVNEIDQKD GLTMDFTTAI
     GNVLSVNGEI KESSDTFSSV CSERKSSSIQ KKIYCDSSSN CFLHDDYYKS AVIYDDDNTV
     DMNLTKTVPY VLEVNNLSSK KKEETRTSDQ CNDITSNIDM TKLFDTKLKS PQRILRNGVL
     AIDALFGKKA LNTNNIRRIS GISVPVQLGS PKAAELLKSR KSMSGFEEMK LAGLGSPANK
     IVIGKKSMWE NEVAKVCTSI LNDFDIKSRI IQLTPKKNDT LSQSLAIQNV LKSATFQDSG
     SELKRNCENT LNNIYVFSPV KKNCNNSPNF KKNEYSDHLV EMQDENNFLS PITLTEFLKI
     TSISFLDGLT TTKRRETTFF PYLAPKPPNL KELIYTASLT LPVLELYQFS CKELQKYIEE
     GKEVINKIEE DTSEENPLLF REYISATHDI RVIMDGQFKL VKNYSRLYAK GIWYEWRDKL
     LLGLKEGLQN NLEGLKKDEL IINDIKPVLN TCFPLIKLKF ESLKEQLNHL RMIKEEINQC
     DQKELREVWS SISRVNEEIQ RNVEKIEDIN KNIYEIDNQL NKLSEKQIIL DREIEEYKKA
     TEANRCFEKE EIENIKRTLE TLKTITGWEA KSFSQDTVVF IYLGVIETTF NFIQNNVSIK
     WNEDIKDKIR MFFFHYLEKI LEKCTIKEAL PLISRIWYIA TSIWSEFCLL KVRYPMLYNL
     TIEDGQPLLE ITTKVFLPLY FLKIFVTFKL RYSIVYEYPN LSNNDFIDIN VIYGNVNVSR
     ISKIILDKVL TGGIKALITA CDEF
//