ID A0A0W4ZEM7_PNEJ7 Unreviewed; 498 AA.
AC A0A0W4ZEM7;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=SET domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=T551_03290 {ECO:0000313|EMBL:KTW26828.1};
OS Pneumocystis jirovecii (strain RU7) (Human pneumocystis pneumonia agent).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Pneumocystomycetes; Pneumocystaceae; Pneumocystis.
OX NCBI_TaxID=1408657 {ECO:0000313|EMBL:KTW26828.1, ECO:0000313|Proteomes:UP000053447};
RN [1] {ECO:0000313|Proteomes:UP000053447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RU7 {ECO:0000313|Proteomes:UP000053447};
RX PubMed=26899007; DOI=10.1038/ncomms10740;
RA Ma L., Chen Z., Huang D.W., Kutty G., Ishihara M., Wang H., Abouelleil A.,
RA Bishop L., Davey E., Deng R., Deng X., Fan L., Fantoni G., Fitzgerald M.,
RA Gogineni E., Goldberg J.M., Handley G., Hu X., Huber C., Jiao X., Jones K.,
RA Levin J.Z., Liu Y., Macdonald P., Melnikov A., Raley C., Sassi M.,
RA Sherman B.T., Song X., Sykes S., Tran B., Walsh L., Xia Y., Yang J.,
RA Young S., Zeng Q., Zheng X., Stephens R., Nusbaum C., Birren B.W.,
RA Azadi P., Lempicki R.A., Cuomo C.A., Kovacs J.A.;
RT "Genome analysis of three Pneumocystis species reveals adaptation
RT mechanisms to life exclusively in mammalian hosts.";
RL Nat. Commun. 7:10740-10740(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTW26828.1}.
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DR EMBL; LFWA01000016; KTW26828.1; -; Genomic_DNA.
DR RefSeq; XP_018228159.1; XM_018375553.1.
DR AlphaFoldDB; A0A0W4ZEM7; -.
DR STRING; 1408657.A0A0W4ZEM7; -.
DR GeneID; 28941808; -.
DR VEuPathDB; FungiDB:T551_03290; -.
DR eggNOG; KOG2084; Eukaryota.
DR OrthoDB; 166337at2759; -.
DR Proteomes; UP000053447; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.220.160; -; 1.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR12197:SF251; EG:BACR7C10.4 PROTEIN; 1.
DR PANTHER; PTHR12197; HISTONE-LYSINE N-METHYLTRANSFERASE SMYD; 1.
DR Pfam; PF00856; SET; 1.
DR Pfam; PF01753; zf-MYND; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000053447};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT DOMAIN 9..245
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 55..101
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
SQ SEQUENCE 498 AA; 58995 MW; B16E88649A6A98BE CRC64;
MDSQKNQEFP VEIKNHKTLK GYGLYSKKRF AEGEEIFIVK PLVAVLDEKH IKNTCSNCFI
SEEDKDDDIF HLIQCKGCKI LQYCCQKCQK EDWEIFHQYE CTFFLSKSPK IVPGSIRICM
RLIFYGRCYP SSLEWNTIMD LESHRSEIMS SEKGDVIWML SKGIQNFTNE MNETFVLDLF
CKIMINSFSL MTSSYDTIGT AIDPIISRIN HSCYPNTALV FDRNTVALRS LQKILPNQEI
TVSYIDIYNT QKNRHDELLS RYYFSCKCTR CIVSDGFESY IVLKKEMTSN TFSYLETIIN
RALSEKNIYL FKALSMLHRL KGWNSTIYPL NELHRFALNY FLDENNFHNA LYHGLFIYLV
GSSVYNQYIS NFNPLYVTQI YLLVRLMIYQ ASENDQKQFK WLDTEKIMKY AYKLLYELVE
LSYKSHGLSS RFSKRIQKTF KETDEDISFC DWGKRWQLIL KNDPRNPQIK EECSRIEDDL
FLELKKYIGE LCNRNYEK
//
