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Database: UniProt
Entry: A0A0W4ZFT2_PNEJ7
LinkDB: A0A0W4ZFT2_PNEJ7
Original site: A0A0W4ZFT2_PNEJ7 
ID   A0A0W4ZFT2_PNEJ7        Unreviewed;        88 AA.
AC   A0A0W4ZFT2;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   16-JAN-2019, entry version 16.
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 9 {ECO:0000256|RuleBase:RU364145};
DE   AltName: Full=Mediator complex subunit 9 {ECO:0000256|RuleBase:RU364145};
GN   Name=MED9 {ECO:0000256|RuleBase:RU364145};
GN   ORFNames=T551_03219 {ECO:0000313|EMBL:KTW27225.1};
OS   Pneumocystis jirovecii (strain RU7) (Human pneumocystis pneumonia
OS   agent).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Pneumocystidomycetes; Pneumocystidaceae; Pneumocystis.
OX   NCBI_TaxID=1408657 {ECO:0000313|EMBL:KTW27225.1, ECO:0000313|Proteomes:UP000053447};
RN   [1] {ECO:0000313|Proteomes:UP000053447}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RU7 {ECO:0000313|Proteomes:UP000053447};
RX   PubMed=26899007; DOI=10.1038/ncomms10740;
RA   Ma L., Chen Z., Huang D.W., Kutty G., Ishihara M., Wang H.,
RA   Abouelleil A., Bishop L., Davey E., Deng R., Deng X., Fan L.,
RA   Fantoni G., Fitzgerald M., Gogineni E., Goldberg J.M., Handley G.,
RA   Hu X., Huber C., Jiao X., Jones K., Levin J.Z., Liu Y., Macdonald P.,
RA   Melnikov A., Raley C., Sassi M., Sherman B.T., Song X., Sykes S.,
RA   Tran B., Walsh L., Xia Y., Yang J., Young S., Zeng Q., Zheng X.,
RA   Stephens R., Nusbaum C., Birren B.W., Azadi P., Lempicki R.A.,
RA   Cuomo C.A., Kovacs J.A.;
RT   "Genome analysis of three Pneumocystis species reveals adaptation
RT   mechanisms to life exclusively in mammalian hosts.";
RL   Nat. Commun. 7:10740-10740(2016).
CC   -!- FUNCTION: Component of the Mediator complex, a coactivator
CC       involved in the regulated transcription of nearly all RNA
CC       polymerase II-dependent genes. Mediator functions as a bridge to
CC       convey information from gene-specific regulatory proteins to the
CC       basal RNA polymerase II transcription machinery. Mediator is
CC       recruited to promoters by direct interactions with regulatory
CC       proteins and serves as a scaffold for the assembly of a functional
CC       preinitiation complex with RNA polymerase II and the general
CC       transcription factors. {ECO:0000256|RuleBase:RU364145}.
CC   -!- SUBUNIT: Component of the Mediator complex.
CC       {ECO:0000256|RuleBase:RU364145}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU364145}.
CC   -!- SIMILARITY: Belongs to the Mediator complex subunit 9 family.
CC       {ECO:0000256|RuleBase:RU364145}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KTW27225.1}.
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DR   EMBL; LFWA01000015; KTW27225.1; -; Genomic_DNA.
DR   RefSeq; XP_018228381.1; XM_018375482.1.
DR   EnsemblFungi; KTW27225; KTW27225; T551_03219.
DR   GeneID; 28941737; -.
DR   OrthoDB; 1640727at2759; -.
DR   Proteomes; UP000053447; Unassembled WGS sequence.
DR   GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR   GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   InterPro; IPR011425; Med9.
DR   Pfam; PF07544; Med9; 1.
PE   3: Inferred from homology;
KW   Activator {ECO:0000256|RuleBase:RU364145};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000053447};
KW   Nucleus {ECO:0000256|RuleBase:RU364145};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053447};
KW   Transcription {ECO:0000256|RuleBase:RU364145};
KW   Transcription regulation {ECO:0000256|RuleBase:RU364145}.
FT   COILED       12     46       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   88 AA;  10223 MW;  FB0ACF21E864E858 CRC64;
     MDLSSTNLIP QIIRILQIMK NKEENIKEFN KEISNLHQQI SNIRKMLQSL PGKDLSILDQ
     EEIIQGLEKQ ISIQKKLLAE INVVEQDK
//
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