ID A0A0W4ZRZ4_PNEJ7 Unreviewed; 615 AA.
AC A0A0W4ZRZ4;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Rad21/Rec8-like protein N-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=T551_01215 {ECO:0000313|EMBL:KTW31142.1};
OS Pneumocystis jirovecii (strain RU7) (Human pneumocystis pneumonia agent).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Pneumocystomycetes; Pneumocystaceae; Pneumocystis.
OX NCBI_TaxID=1408657 {ECO:0000313|EMBL:KTW31142.1, ECO:0000313|Proteomes:UP000053447};
RN [1] {ECO:0000313|Proteomes:UP000053447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RU7 {ECO:0000313|Proteomes:UP000053447};
RX PubMed=26899007; DOI=10.1038/ncomms10740;
RA Ma L., Chen Z., Huang D.W., Kutty G., Ishihara M., Wang H., Abouelleil A.,
RA Bishop L., Davey E., Deng R., Deng X., Fan L., Fantoni G., Fitzgerald M.,
RA Gogineni E., Goldberg J.M., Handley G., Hu X., Huber C., Jiao X., Jones K.,
RA Levin J.Z., Liu Y., Macdonald P., Melnikov A., Raley C., Sassi M.,
RA Sherman B.T., Song X., Sykes S., Tran B., Walsh L., Xia Y., Yang J.,
RA Young S., Zeng Q., Zheng X., Stephens R., Nusbaum C., Birren B.W.,
RA Azadi P., Lempicki R.A., Cuomo C.A., Kovacs J.A.;
RT "Genome analysis of three Pneumocystis species reveals adaptation
RT mechanisms to life exclusively in mammalian hosts.";
RL Nat. Commun. 7:10740-10740(2016).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the rad21 family.
CC {ECO:0000256|ARBA:ARBA00009870}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTW31142.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LFWA01000005; KTW31142.1; -; Genomic_DNA.
DR RefSeq; XP_018230132.1; XM_018373478.1.
DR AlphaFoldDB; A0A0W4ZRZ4; -.
DR STRING; 1408657.A0A0W4ZRZ4; -.
DR GeneID; 28939733; -.
DR VEuPathDB; FungiDB:T551_01215; -.
DR eggNOG; KOG1213; Eukaryota.
DR OrthoDB; 5481351at2759; -.
DR Proteomes; UP000053447; Unassembled WGS sequence.
DR GO; GO:0008278; C:cohesin complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR CDD; cd21788; Rad21_Rec8_M_SpRad21p-like; 1.
DR Gene3D; 1.10.10.580; Structural maintenance of chromosome 1. Chain E; 1.
DR InterPro; IPR039781; Rad21/Rec8-like.
DR InterPro; IPR006909; Rad21/Rec8_C_eu.
DR InterPro; IPR006910; Rad21_Rec8_N.
DR InterPro; IPR023093; ScpA-like_C.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12585:SF69; FI11703P; 1.
DR PANTHER; PTHR12585; SCC1 / RAD21 FAMILY MEMBER; 1.
DR Pfam; PF04824; Rad21_Rec8; 1.
DR Pfam; PF04825; Rad21_Rec8_N; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000053447}.
FT DOMAIN 1..102
FT /note="Rad21/Rec8-like protein N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04825"
FT DOMAIN 533..583
FT /note="Rad21/Rec8-like protein C-terminal eukaryotic"
FT /evidence="ECO:0000259|Pfam:PF04824"
SQ SEQUENCE 615 AA; 69231 MW; 8A3B934B2DF4465A CRC64;
MFYSETILSK KGPLAKIWLA AHWEKKLSKS QFLQTNIKQT VNAIVNQDQI PIALRLSGQL
LLGVVKVYSR KTRYLLEDCN EALIKIKMAF RQGNVDLPAS NNMNIALQSA QLVLPETITE
FDLLIPDPTF NIMDIDEIPE PSSFSYVSKK QDITLISALD PSIEVGRGHQ LNLVDDPLVQ
IDESQKIDLD LGIGDNDGLQ NDISVEIGRD RVPESRFSQE FSNIIGSEKD VNDENIFLTD
VDMGNHLDTI HSNDMHDPLE PVTEFSIHQL EAIDQNNGLI LEDRERSISG TTSTLTAEIL
EFDELQAGIP ESNDKTTQSK THQSRYKRVL EDSAIEISSK AFSSQLRNTS SITKQNKLLS
SDPIFLTLTQ LQTSGKFATH IFEPSNVHPS IVSLLNPGYI SFVQSNLFKR KRVENINQND
YDSANVSKHA KIDTTPINES RIDADLSNNN LGNFELENSN ILLPVDDNSI SIYDNSEINA
DQVSKSSIYD FSIKQDKEIE LVNESTFDSG IYDDLDLIST LRNRFNLEKN ASKNTISFND
LIENASRIDV SKKFLEILVL ATKNLINIEQ KESYGDIRIS ASKELFDNNI KILLEKDQNI
QNNVKKINMV KSSNN
//
